5-METHOXYFLAVANONE

Base Information

• Chemical Name: 5-METHOXYFLAVANONE
• CAS No.: 55947-36-9
• Molecular Formula: C16H14O3
• Molecular Weight: 254.285
• Hs Code.: 2932999099
• Mol file: 55947-36-9.mol

Synonyms:METHOXYFLAVANONE, 5-;5-METHOXYFLAVANONE;METHOXYFLAVANONE, 5-(P)

Chemical Property of 5-METHOXYFLAVANONE

Chemical Property:

• Vapor Pressure: 8.28E-08mmHg at 25°C
• Melting Point: 144-145°C
• Refractive Index: 1.587
• Boiling Point: 436.1°C at 760 mmHg
• Flash Point: 209.4°C
• PSA: 35.53000
• Density: 1.199g/cm³
• LogP: 3.40170

Purity/Quality:

98% ^*data from raw suppliers

5-Methoxyflavanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-METHOXYFLAVANONE

There total 10 articles about 5-METHOXYFLAVANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2'-Hydroxy-6'-methoxychalcone (40524-67-2,42079-68-5) → 5-methoxyflavanone (55947-36-9,123931-32-8)

Guidance literature:

With piperidine; potassium hydroxide; In water; at 20 ℃; for 0.0333333h;

DOI:10.1080/00397911.2011.621096

Reference yield: 83.0%

(E)-1-(2-hydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one (40524-67-2,42079-68-5) → 5-methoxyflavanone (55947-36-9,123931-32-8)

Guidance literature:

With cesium fluoride; In water; acetonitrile; at 80 ℃; for 2h;

DOI:10.1016/j.tetlet.2021.153480

Reference yield: 64.0%

5-methoxychroman-4-one (863309-86-8) + phenylboronic acid (98-80-6) → 5-methoxyflavanone (55947-36-9,123931-32-8)

Guidance literature:

5-methoxychroman-4-one; With [2,2]bipyridinyl; palladium(II) trifluoroacetate; oxygen; In 1,4-dioxane; dimethyl sulfoxide; at 100 ℃;

phenylboronic acid; With oxygen; trifluoroacetic acid; In 1,4-dioxane; dimethyl sulfoxide; at 80 ℃;

DOI:10.1021/acs.joc.9b01162

upstream raw materials:

(E)-1-(2-hydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one

2'-hydroxy-6'-methoxyacetophenone

benzaldehyde

5-methoxyflavone

Downstream raw materials:

8-bromo-5-methoxy-2-phenyl-chromen-4-one

(E)-1-(2-hydroxy-6-methoxyphenyl)-3-phenylprop-2-en-1-one

6-hydroxy-5-methoxy-2-phenyl-chroman-4-one

5-methoxy-8-bromo-flavanone