1-Amino-3-(4-methoxyphenoxy)propan-2-ol

Base Information

• Chemical Name: 1-Amino-3-(4-methoxyphenoxy)propan-2-ol
• CAS No.: 5002-93-7
• Molecular Formula: C10H15NO3
• Molecular Weight: 197.234
• Hs Code.: 2922509090
• DSSTox Substance ID: DTXSID20370691
• Mol file: 5002-93-7.mol

Synonyms:1-amino-3-(4-methoxyphenoxy)propan-2-ol;5002-93-7;1-Amino-3-(4-methoxy-phenoxy)-propan-2-ol;4-(3-Amino-2-hydroxypropoxy)anisole;Maybridge1_002199;Oprea1_351577;Oprea1_368403;1,5-pentanedioldimethacrylate;SCHEMBL4944194;HMS547L21;DTXSID20370691;KFQPRNVTVMCYEH-UHFFFAOYSA-N;BBL028388;MFCD00205693;STL146371;AKOS000149681;AKOS016045797;PS-3065;SB84117;BP-10311;BB 0254946;CS-0207028;FT-0607320;(2rs)-1-amino-3-(4methoxyphenoxy)-2-propanol;(2rs)-1-amino-3-(4-methoxyphenoxy)-2-propanol;J-504185;1-Amino-3-(4-methoxyphenoxy)-2-propanol, AldrichCPR;Z56919203

Chemical Property of 1-Amino-3-(4-methoxyphenoxy)propan-2-ol

Chemical Property:

• Vapor Pressure: 4.33E-06mmHg at 25°C
• Melting Point: 110-112
• Refractive Index: 1.539
• Boiling Point: 368.8°Cat760mmHg
• Flash Point: 176.9°C
• PSA: 64.71000
• Density: 1.146g/cm³
• LogP: 1.09390
• XLogP3: 0.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 197.10519334
• Heavy Atom Count: 14
• Complexity: 146

Purity/Quality:

98%min ^*data from raw suppliers

1-Amino-3-(4-methoxyphenoxy)propan-2-ol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: R34:Causes burns.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)OCC(CN)O

Technology Process of 1-Amino-3-(4-methoxyphenoxy)propan-2-ol

There total 1 articles about 1-Amino-3-(4-methoxyphenoxy)propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ (2RS)-1-amino-3-(4-methoxyphenoxy)-2-propanol (5002-93-7)

Guidance literature:

DOI:10.1007/BF00779124

Reference yield: 49.0%

phenethyl isocyanate (1943-82-4) + (2RS)-1-amino-3-(4-methoxyphenoxy)-2-propanol (5002-93-7) → N-[2-hydroxy-3-(4-methoxyphenoxy)propyl]-N'-2-phenethyl-urea

Guidance literature:

In acetonitrile; at 27 ℃; for 8.25h;

Reference yield: 31.0%

(2RS)-1-amino-3-(4-methoxyphenoxy)-2-propanol (5002-93-7) + 4-(4-chlorophenyl)-4-oxobutanoic acid (3984-34-7) → (2S,7aR)-7a-(4-Chloro-phenyl)-2-(4-methoxy-phenoxymethyl)-tetrahydro-pyrrolo[2,1-b]oxazol-5-one

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 16h; Heating;

DOI:10.1021/jm9803121