2-bromo-1-(1-methyl-1H-benzimidazol-2-yl)-1-ethanone

Base Information

Chemical Name:2-bromo-1-(1-methyl-1H-benzimidazol-2-yl)-1-ethanone
CAS No.:56653-43-1
Molecular Formula:C10H9BrN2O
Molecular Weight:253.098
Hs Code.:2933990090
DSSTox Substance ID:DTXSID60383548
Nikkaji Number:J1.172.623B
Wikidata:Q82175320
Mol file:56653-43-1.mol

Synonyms:56653-43-1;2-bromo-1-(1-methyl-1H-benzimidazol-2-yl)-1-ethanone;2-bromo-1-(1-methylbenzimidazol-2-yl)ethanone;2-Bromo-1-(1-methyl-1H-benzo[d]imidazol-2-yl)ethanone;2-Bromo-1-(1-methyl-1H-benzimidazol-2-yl)ethanone;2-bromo-1-(1-methyl-1h-benzoimidazol-2-yl)-ethanone;SCHEMBL2097340;DTXSID60383548;KHFRWYRANOMZCP-UHFFFAOYSA-N;MFCD06200854;MS-22247;1-Methyl-2-(bromoacetyl)-1H-benzimidazole;CS-0365293;FT-0746910;A923916;J-508135;2-bromo-1-(1-methyl-1H-benzoimidazol-2-yl)ethanone;2-bromo-1-(1-methyl-1H-1,3-benzodiazol-2-yl)ethan-1-one;2-Bromo-1-(1-methyl-1H-benzo[d]imidazol-2-yl)ethan-1-one

Suppliers and Price of 2-bromo-1-(1-methyl-1H-benzimidazol-2-yl)-1-ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Bromo-1-(1-methyl-1H-benzimidazol-2-yl)ethanone 95%
1g
$ 414.00

Crysdot
2-Bromo-1-(1-methyl-1H-benzo[d]imidazol-2-yl)ethanone 97%
5g
$ 769.00

Atlantic Research Chemicals
2-Bromo-1-(1-methyl-1H-benzimidazol-2-yl)ethanone 95%
Price $/1gm:
$ 142.92

American Custom Chemicals Corporation
2-BROMO-1-(1-METHYL-1H-BENZIMIDAZOL-2-YL)-1-ETHANONE 95.00%
5G
$ 1461.37

American Custom Chemicals Corporation
2-BROMO-1-(1-METHYL-1H-BENZIMIDAZOL-2-YL)-1-ETHANONE 95.00%
1G
$ 848.93

American Custom Chemicals Corporation
2-BROMO-1-(1-METHYL-1H-BENZIMIDAZOL-2-YL)-1-ETHANONE 95.00%
250MG
$ 654.89

AK Scientific
2-Bromo-1-(1-methyl-1H-benzimidazol-2-yl)-1-ethanone
1g
$ 608.00

Total 10 raw suppliers

Chemical Property of 2-bromo-1-(1-methyl-1H-benzimidazol-2-yl)-1-ethanone

Chemical Property:

Vapor Pressure:9.96E-06mmHg at 25°C
Melting Point:100 °C
Refractive Index:1.65
Boiling Point:371.9°Cat760mmHg
PKA:2.99±0.10(Predicted)
Flash Point:178.7°C
PSA：34.89000
Density:1.57g/cm³
LogP:2.15090
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:251.98983
Heavy Atom Count:14
Complexity:234

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-1-(1-methyl-1H-benzimidazol-2-yl)ethanone 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2=CC=CC=C2N=C1C(=O)CBr

Technology Process of 2-bromo-1-(1-methyl-1H-benzimidazol-2-yl)-1-ethanone

There total 6 articles about 2-bromo-1-(1-methyl-1H-benzimidazol-2-yl)-1-ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 942-25-6
2-acetyl-1-methylbenzimidazole

: 56653-43-1
2-bromo-1-(1-methyl-1H-benzo[d]imidazol-2-yl)ethan-1-one

Guidance literature:: With bromine; acetic acid; at 20 - 80 ℃;
DOI:10.1002/jhet.3407

Reference yield:

: 942-25-6
2-acetyl-1-methylbenzimidazole

: 56653-45-3
2,2-dibromo-1-(1-methyl-1H-benzoimidazol-2-yl)-ethanone

: 56653-43-1
2-bromo-1-(1-methyl-1H-benzo[d]imidazol-2-yl)ethan-1-one

Guidance literature:: With bromine; In acetic acid; at 100 ℃;
DOI:10.1080/00397910902985465

Reference yield:

: 939-70-8
2-acetylbenzimidazole

: 56653-43-1
2-bromo-1-(1-methyl-1H-benzo[d]imidazol-2-yl)ethan-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / TEBAC; K₂CO₃ / acetonitrile / 3 h / 20 °C

2: 70 percent / Br₂ / acetic acid / 3 h / 100 °C

With N-benzyl-N,N,N-triethylammonium chloride; bromine; potassium carbonate; In acetic acid; acetonitrile; 1: Methylation / 2: Bromination;