2-(5-methoxy-1H-indol-3-yl)acetohydrazide

Base Information

Chemical Name:2-(5-methoxy-1H-indol-3-yl)acetohydrazide
CAS No.:57000-48-3
Molecular Formula:C11H13N3O2
Molecular Weight:219.24
Hs Code.:
DSSTox Substance ID:DTXSID20481130
Wikidata:Q82316370
Mol file:57000-48-3.mol

Synonyms:2-(5-methoxy-1H-indol-3-yl)acetohydrazide;57000-48-3;5-METHOXYINDOLE-3-ACETIC ACID HYDRAZIDE;(5-METHOXY-1H-INDOL-3-YL)-ACETIC ACID HYDRAZIDE;SCHEMBL6862429;DTXSID20481130;M-3477;(5-METHOXY-1H-INDOL-3-YL)-ACETICACIDHYDRAZIDE

Suppliers and Price of 2-(5-methoxy-1H-indol-3-yl)acetohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(5-METHOXY-1H-INDOL-3-YL)-ACETIC ACID HYDRAZIDE 95.00%
5MG
$ 497.35

Total 4 raw suppliers

Chemical Property of 2-(5-methoxy-1H-indol-3-yl)acetohydrazide

Chemical Property:

Vapor Pressure:9.37E-12mmHg at 25°C
Refractive Index:1.657
Boiling Point:540.6°Cat760mmHg
Flash Point:280.8°C
PSA：80.14000
Density:1.302g/cm³
LogP:1.80010
XLogP3:0.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:219.100776666
Heavy Atom Count:16
Complexity:260

Purity/Quality:

99% ^*data from raw suppliers

(5-METHOXY-1H-INDOL-3-YL)-ACETIC ACID HYDRAZIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)NC=C2CC(=O)NN

Technology Process of 2-(5-methoxy-1H-indol-3-yl)acetohydrazide

There total 3 articles about 2-(5-methoxy-1H-indol-3-yl)acetohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 57000-49-4
(5-methoxy-1H-indol-3-yl)acetic acid ethyl ester

: 57000-48-3
2-(5-methoxy-1H-indol-3-yl)acetohydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; at 155 ℃; for 0.75h; Microwave irradiation;
DOI:10.1021/acs.jmedchem.5b00245

Reference yield:

: 3471-31-6,142396-09-6
5-methoxy-1H-indole-3-acetic acid

: 57000-48-3
2-(5-methoxy-1H-indol-3-yl)acetohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid / 2 h / Reflux

2: hydrazine hydrate / ethanol / 0.75 h / 155 °C / Microwave irradiation

With sulfuric acid; hydrazine hydrate; In ethanol;
DOI:10.1021/acs.jmedchem.5b00245