N-1H-imidazol-2-ylacetamide

Base Information

• Chemical Name: N-1H-imidazol-2-ylacetamide
• CAS No.: 52737-49-2
• Molecular Formula: C₅H₇N₃O
• Molecular Weight: 125.13
• Mol file: 52737-49-2.mol

Synonyms:N-1H-imidazol-2-ylacetamide

Chemical Property of N-1H-imidazol-2-ylacetamide

Chemical Property:

• Refractive Index: 1.62
• PSA: 57.78000
• Density: 1.33g/cm³
• LogP: 0.44110
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

N-1H-Imidazol-2-ylacetamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: N-1H-Imidazol-2-ylacetamide is a useful research chemical.

Technology Process of N-1H-imidazol-2-ylacetamide

There total 5 articles about N-1H-imidazol-2-ylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

acetic anhydride (108-24-7) + 2-aminoimidazole hemisulfate (1450-93-7,36946-29-9,42383-61-9) → 2-acetamidoimidazole (52737-49-2)

Guidance literature:

With triethylamine; at 25 ℃; for 42h;

DOI:10.1080/07328319908044860

Reference yield:

acetic anhydride (108-24-7) → 2-acetamidoimidazole (52737-49-2)

Guidance literature:

With sodium acetate;

Reference yield:

2-nitro-1H-imidazole (527-73-1) + acetic anhydride (108-24-7) → 2-acetamidoimidazole (52737-49-2)

Guidance literature:

With hydrogenchloride; acetic acid; tin(ll) chloride;

upstream raw materials:

2-nitro-1H-imidazole

acetic anhydride

2-amino-1H-imidazole hydrochloride

2-aminoimidazole hemisulfate

Downstream raw materials:

1-(2,3,5-tri-O-benzoyl-α-D-arabinofuranosyl)-2-acetamidoimidazole