3,5-DICHLOROACETOACETANILID

Base Information

• Chemical Name: 3,5-DICHLOROACETOACETANILID
• CAS No.: 52793-04-1
• Molecular Formula: C10H9Cl2NO2
• Molecular Weight: 246.09
• Hs Code.: 2924299090
• Mol file: 52793-04-1.mol

Synonyms:3,5-DICHLOROACETOACETANILID;3,5-Dichloroacetoacetanilide

Chemical Property of 3,5-DICHLOROACETOACETANILID

Chemical Property:

• Vapor Pressure: 3.4E-07mmHg at 25°C
• Refractive Index: 1.59
• Boiling Point: 418°C at 760 mmHg
• Flash Point: 206.6°C
• PSA: 46.17000
• Density: 1.393g/cm³
• LogP: 2.98400

Purity/Quality:

97% ^*data from raw suppliers

3,5-DICHLOROACETOACETANILID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-DICHLOROACETOACETANILID

There total 2 articles about 3,5-DICHLOROACETOACETANILID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl acetoacetate (141-97-9) + 3,5-Dichloroaniline (626-43-7) → 3-oxo-N-(3',5'-dichlorophenyl)butanamide (52793-04-1)

Guidance literature:

In toluene; at 80 ℃; for 2h;

DOI:10.1002/cbdv.201800105

Reference yield:

→ 3-oxo-N-(3',5'-dichlorophenyl)butanamide (52793-04-1)

Guidance literature:

Reference yield: 58.0%

vanillin (121-33-5,8014-42-4) + 3-oxo-N-(3',5'-dichlorophenyl)butanamide (52793-04-1) → (4E)-N-(3,5-dichlorophenyl)-5-(4-hydroxy-3-methoxyphenyl)-3-oxopent-4-enamide

Guidance literature:

3-oxo-N-(3',5'-dichlorophenyl)butanamide; With boron trioxide; In ethyl acetate; at 20 ℃; for 0.5h; Inert atmosphere;

vanillin; With boric acid tributyl ester; In ethyl acetate; for 1h; Further stages; Inert atmosphere;

DOI:10.1002/cbdv.201800105

upstream raw materials:

ethyl acetoacetate

3,5-Dichloroaniline

Downstream raw materials:

N-(3,5-dichloro-phenyl)-2-hydroxyimino-3-oxo-butyramide

2-furan-2-yl-3-hydroxy-5-methyl-3H-imidazole-4-carboxylic acid 3,5-dichloro-anilide

Refernces

• 1、 -. "4-isoxazolecarboxamide derivatives". . . Retrieved 2008/06/13.