3-(2-Chlorophenyl)-1-naphthalen-2-ylprop-2-en-1-one

Base Information

Chemical Name:3-(2-Chlorophenyl)-1-naphthalen-2-ylprop-2-en-1-one
CAS No.:57221-64-4
Molecular Formula:C19H13ClO
Molecular Weight:292.765
Hs Code.:
DSSTox Substance ID:DTXSID70379816

Synonyms:57221-64-4;3-(2-chlorophenyl)-1-naphthalen-2-ylprop-2-en-1-one;DTXSID70379816;FT-0726058;17BETA-HYDROXY-4-ANDROSTEN-3-ONE3-[O-CARBOXYMETHYL]OXIME

Suppliers and Price of 3-(2-Chlorophenyl)-1-naphthalen-2-ylprop-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-(2-CHLOROPHENYL)-1-(2-NAPHTHYL)PROP-2-EN-1-ONE 95.00%
5MG
$ 495.59

Total 4 raw suppliers

Chemical Property of 3-(2-Chlorophenyl)-1-naphthalen-2-ylprop-2-en-1-one

Chemical Property:

PSA：17.07000
LogP:5.38930
XLogP3:5.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:292.0654927
Heavy Atom Count:21
Complexity:389

Purity/Quality:

99% ^*data from raw suppliers

3-(2-CHLOROPHENYL)-1-(2-NAPHTHYL)PROP-2-EN-1-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C=C(C=CC2=C1)C(=O)C=CC3=CC=CC=C3Cl

Technology Process of 3-(2-Chlorophenyl)-1-naphthalen-2-ylprop-2-en-1-one

There total 4 articles about 3-(2-Chlorophenyl)-1-naphthalen-2-ylprop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 29.0%

: 89-98-5
2-chloro-benzaldehyde

: 93-08-3
methyl 2-naphthyl ketone

: 57221-64-4
(2E)-1-(2-naphthyl)-3-(2-chlorophenyl)-2-propen-1-one

Guidance literature:: With potassium hydroxide; In methanol; at 20 ℃; for 24h;
DOI:10.1016/j.bmc.2010.09.025

Reference yield:

: 89-98-5
2-chloro-benzaldehyde

: 93-08-3
methyl 2-naphthyl ketone

: 57221-64-4
(E)-3-(2-Chloro-phenyl)-1-naphthalen-2-yl-propenone

Guidance literature:: With sodium hydroxide; In ethanol; water; at 20 ℃; for 12h;
DOI:10.1002/cbdv.202000025

Reference yield:

: 7228-47-9
2-(2-naphthyl)ethanol

: 57221-64-4
(E)-3-(2-Chloro-phenyl)-1-naphthalen-2-yl-propenone

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / toluene / 14 h / 110 °C / Reflux; Inert atmosphere

2: sodium hydroxide / water; ethanol / 12 h / 20 °C

With potassium tert-butylate; sodium hydroxide; In ethanol; water; toluene;
DOI:10.1002/cbdv.202000025