(3aS,6aR)-3,3a,6,6a-Tetrahydro-2H-cyclopenta[b]furan-2-one

Base Information

• Chemical Name: (3aS,6aR)-3,3a,6,6a-Tetrahydro-2H-cyclopenta[b]furan-2-one
• CAS No.: 54483-22-6
• Molecular Formula: C₇H₈O₂
• Molecular Weight: 124.139
• Hs Code.: 2932209090
• European Community (EC) Number: 814-140-2
• DSSTox Substance ID: DTXSID00969663
• Nikkaji Number: J28.179D
• Wikidata: Q82952686
• ChEMBL ID: CHEMBL452408
• Mol file: 54483-22-6.mol

Synonyms:(3aS,6aR)-3,3a,6,6a-Tetrahydro-2H-cyclopenta[b]furan-2-one;54483-22-6;26054-46-6;(+)-cis-2-Oxabicyclo[3.3.0]oct-6-en-3-one;(1R,5S)-2-Oxabicyclo[3.3.0]oct-6-en-3-one;(3aS,6aR)-3,3a,6,6a-tetrahydrocyclopenta[b]furan-2-one;(1R,5S)-oxabicyclooctenone;CHEMBL452408;SCHEMBL3910871;(+)-(1R,5S)-2-Oxabicyclo[3.3.0]oct-6-en-3-one;DTXSID00969663;RYBPGUMSFWGGLP-PHDIDXHHSA-N;AKOS006238073;AC-28169;J-650325;(3aS,6aR)-2H,3H,3aH,6H,6aH-cyclopenta[b]furan-2-one;(3as,6ar)-3,3a,6,6a-tetrahydro-2h-cyclo-penta[b]furan-2-one;(3aS, 6aR)-3, 3a, 6, 6a-tetrahydro-2H-cyclopenta[b]furan-2-one

Chemical Property of (3aS,6aR)-3,3a,6,6a-Tetrahydro-2H-cyclopenta[b]furan-2-one

Chemical Property:

• Appearance/Colour: slightly beige crystals
• Vapor Pressure: 0.01mmHg at 25°C
• Melting Point: 45-48 °C(lit.)
• Refractive Index: 1.4906 (estimate)
• Boiling Point: 263.1 °C at 760 mmHg
• Flash Point: 104 °C
• PSA: 26.30000
• Density: 1.196 g/cm³
• LogP: 0.87800
• Storage Temp.: 0-6°C
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 124.052429494
• Heavy Atom Count: 9
• Complexity: 172

Purity/Quality:

99%,98%, ^*data from raw suppliers

(1R,5S)-2-OXABICYCLO(3.3.0)OCT-6-EN-3-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1C=CC2C1OC(=O)C2
• Isomeric SMILES: C1C=C[C@H]2[C@@H]1OC(=O)C2

Technology Process of (3aS,6aR)-3,3a,6,6a-Tetrahydro-2H-cyclopenta[b]furan-2-one

There total 54 articles about (3aS,6aR)-3,3a,6,6a-Tetrahydro-2H-cyclopenta[b]furan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(3aS,6aR)-3,3-dichloro-3,3a,6,6a-tetrahydro-2H-cyclopenta[b]furan-2-one (162425-53-8) → (1R,5S)-2-oxabicyclo[3.3.0]oct-6-en-3-one (34638-25-0,38110-77-9,43119-28-4,54483-22-6,26054-46-6)

Guidance literature:

With ammonium chloride; zinc; In methanol; for 2h; Heating;

DOI:10.1016/S0040-4020(01)96154-X

Reference yield: 93.0%

(1S,5R)-(-)-bicyclo[3.2.0]hept-2-en-6-one (71155-04-9) → (1R,5S)-2-oxabicyclo[3.3.0]oct-6-en-3-one (34638-25-0,38110-77-9,43119-28-4,54483-22-6,26054-46-6)

Guidance literature:

With dihydrogen peroxide; acetic acid; at 0 ℃; for 12h;

DOI:10.1016/S0040-4039(00)97481-1

Reference yield: 68.0%

(3aR,5R,6aR)-(+)-5-Methansulfonsaeure-(2-oxo-hexahydro-2H-cyclopentafuran-5-yl)ester (151910-96-2) → (1R,5S)-2-oxabicyclo[3.3.0]oct-6-en-3-one (34638-25-0,38110-77-9,43119-28-4,54483-22-6,26054-46-6)

Guidance literature:

With pyridine; In benzene; at 240 - 250 ℃; for 0.5h;

upstream raw materials:

bicyclo(3.2.0)hept-2-en-6-one

(1S,5R)-(-)-bicyclo[3.2.0]hept-2-en-6-one

(1R,5S)-bicyclo[3.2.0]hept-2-en-6-one

bicyclo[3.2.0]hept-2-en-6-one

Downstream raw materials:

<3aS(3aα,4α,5β,6aα)>-(+)-5-hydroxy-4-hydroxymethyl-hexahydro-2H-cyclopentafuran-2-one

(3aR,4R,5R,6aR)-5-Iodo-4-(1-methoxy-1-methyl-ethoxy)-hexahydro-cyclopenta[b]furan-2-one

(3aR,4R,6R,6aR)-6-Iodo-4-(1-methoxy-1-methyl-ethoxy)-hexahydro-cyclopenta[b]furan-2-one

2-Oxabicyclo[3,3,0]oct-6-en-3-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

✦Write with AI

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 54483-22-6 (+)-CIS-2-OXABICYCLO[3.3.0]OCT-6-EN-3-ONE

Send

Send

Metric Ton KG G Pound L ML

Send

Send