C-Phenyl-C-thiophen-2-yl-methylamine hydrochloride

Base Information

Chemical Name:C-Phenyl-C-thiophen-2-yl-methylamine hydrochloride
CAS No.:53387-66-9
Molecular Formula:C11H11NS.ClH
Molecular Weight:225.742
Hs Code.:2934999090
European Community (EC) Number:899-537-9
Mol file:53387-66-9.mol

Synonyms:C-Phenyl-C-thiophen-2-yl-methylamine hydrochloride;53387-66-9;AKOS026676146;EN300-30275;PHENYL(THIOPHEN-2-YL)METHANAMINE HYDROCHLORIDE;Z1891773502

Suppliers and Price of C-Phenyl-C-thiophen-2-yl-methylamine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
C-PHENYL-C-THIOPHEN-2-YL-METHYLAMINE HYDROCHLORIDE 95.00%
5MG
$ 505.48

Total 2 raw suppliers

Chemical Property of C-Phenyl-C-thiophen-2-yl-methylamine hydrochloride

Chemical Property:

PSA：54.26000
LogP:4.29850
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:225.0378983
Heavy Atom Count:14
Complexity:154

Purity/Quality:

99% ^*data from raw suppliers

C-PHENYL-C-THIOPHEN-2-YL-METHYLAMINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C2=CC=CS2)N.Cl

Technology Process of C-Phenyl-C-thiophen-2-yl-methylamine hydrochloride

There total 2 articles about C-Phenyl-C-thiophen-2-yl-methylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 53252-10-1
phenyl(thiophen-2-yl)methanone oxime

: 53387-66-9
(RS)-phenyl-(2-thienyl)methylamine hydrochloride

Guidance literature:: With sodium tetrahydroborate; titanium tetrachloride; In 1,2-dimethoxyethane; at 20 ℃; for 48h;
DOI:10.1016/S0968-0896(00)00050-X

Reference yield:

: 135-00-2
2-Benzoylthiophene

: 53387-66-9
(RS)-phenyl-(2-thienyl)methylamine hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / NH₂OH*HCl; Na₂CO₃ / ethanol / 96 h / Heating

2: 60 percent / NaBH₄; TiCl₄ / 1,2-dimethoxy-ethane / 48 h / 20 °C

With sodium tetrahydroborate; hydroxylamine hydrochloride; titanium tetrachloride; sodium carbonate; In 1,2-dimethoxyethane; ethanol; 1: Condensation / 2: Reduction;
DOI:10.1016/S0968-0896(00)00050-X

Reference yield:

: 53387-66-9
(RS)-phenyl-(2-thienyl)methylamine hydrochloride

: (phenyl-thiophen-2-yl-methyl)-carbamic acid 3-(1H-imidazol-4-yl)-propyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: charcoal / ethyl acetate / 4 h / Heating

2: acetonitrile / 4 h / Heating

pyrographite; In ethyl acetate; acetonitrile; 1: Condensation / 2: Addition;
DOI:10.1016/S0968-0896(00)00050-X