3-Methoxy-17-nitroso-7,8-didehydro-4,5-epoxymorphinan-6-ol

Base Information

Chemical Name:3-Methoxy-17-nitroso-7,8-didehydro-4,5-epoxymorphinan-6-ol
CAS No.:77774-24-4
Molecular Formula:C₁₇H₁₈N₂O₄
Molecular Weight:314.341
Hs Code.:
NSC Number:134603
DSSTox Substance ID:DTXSID70998965

Synonyms:77774-24-4;3-methoxy-17-nitroso-7,8-didehydro-4,5-epoxymorphinan-6-ol;NSC134603;DTXSID70998965;NSC-134603;Morphinan-6-ol,8-didehydro-4,5-epoxy-3-methoxy-17-nitroso-, (5.alpha.,6.alpha.)-

Suppliers and Price of 3-Methoxy-17-nitroso-7,8-didehydro-4,5-epoxymorphinan-6-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-Methoxy-17-nitroso-7,8-didehydro-4,5-epoxymorphinan-6-ol

Chemical Property:

Vapor Pressure:5.32E-13mmHg at 25°C
Boiling Point:551.6°Cat760mmHg
Flash Point:287.4°C
Density:1.64g/cm³
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:314.12665706
Heavy Atom Count:23
Complexity:555

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C2C3=C(CC4C5C3(CCN4N=O)C(O2)C(C=C5)O)C=C1

Technology Process of 3-Methoxy-17-nitroso-7,8-didehydro-4,5-epoxymorphinan-6-ol

There total 2 articles about 3-Methoxy-17-nitroso-7,8-didehydro-4,5-epoxymorphinan-6-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.3%

: 76-57-3
codeine

: 77774-24-4
N-demethyl-N-nitrosocodeine

Guidance literature:: With sulfuric acid; sodium nitrite; at 90 ℃; for 2h;

Reference yield:

: 467-15-2,10118-79-3,25318-90-5,131830-12-1
norcodeine

: 77774-24-4
4,5-epoxy-3-methoxy-17-nitroso-morphin-7-en-6-ol

Guidance literature:: With acetic acid; sodium nitrite; N-nitroso-norcodeine;

Reference yield:

: 77774-24-4
N-demethyl-N-nitrosocodeine

: C₂₄H₂₄N₂O₄

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / aq. acetic acid; Zn / 0.5 h / 45 - 50 °C

2: 50.7 percent / ethanol / 28 h / 20 °C

With acetic acid; zinc; In ethanol; 1: Reduction / 2: Condensation;