3-amino-6-chloroquinazolin-4(3H)-one

Base Information

Chemical Name:3-amino-6-chloroquinazolin-4(3H)-one
CAS No.:5584-16-7
Molecular Formula:C8H6ClN3O
Molecular Weight:195.61
Hs Code.:2933990090
DSSTox Substance ID:DTXSID60429253
Wikidata:Q82242240
Mol file:5584-16-7.mol

Synonyms:3-amino-6-chloroquinazolin-4(3H)-one;5584-16-7;3-amino-6-chloroquinazolin-4-one;3-amino-6-chloro-3,4-dihydroquinazolin-4-one;SCHEMBL3755039;DTXSID60429253;ZBLKVISBOLRJDY-UHFFFAOYSA-N;AKOS022529456;3-Amino-6-chloro-4(3H)-quinazolinone;CS-0241775;EN300-23786;Z164708506

Suppliers and Price of 3-amino-6-chloroquinazolin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-amino-6-chloro-3,4-dihydroquinazolin-4-one
50mg
$ 90.00

American Custom Chemicals Corporation
3-AMINO-6-CHLOROQUINAZOLIN-4(3H)-ONE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
3-AMINO-6-CHLOROQUINAZOLIN-4(3H)-ONE 95.00%
1G
$ 453.60

Total 5 raw suppliers

Chemical Property of 3-amino-6-chloroquinazolin-4(3H)-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.72
Boiling Point:399°Cat760mmHg
Flash Point:195.1°C
PSA：60.91000
Density:1.58g/cm³
LogP:1.34490
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:195.0199395
Heavy Atom Count:13
Complexity:256

Purity/Quality:

98%Min ^*data from raw suppliers

3-amino-6-chloro-3,4-dihydroquinazolin-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=C1Cl)C(=O)N(C=N2)N

Technology Process of 3-amino-6-chloroquinazolin-4(3H)-one

There total 3 articles about 3-amino-6-chloroquinazolin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 5584-15-6
5-chloroanthranilic acid hydrazide

: 122-51-0
orthoformic acid triethyl ester

: 5584-16-7
3-Amino-6-chloro-4(3H)-quinazolinone

Guidance literature:: In ethanol; for 24h; Heating;

Reference yield:

: 4743-17-3
5-Chloroisatoic anhydride

: 5584-16-7
3-Amino-6-chloro-4(3H)-quinazolinone

Guidance literature:: Multi-step reaction with 2 steps

1: N₂H₄*H₂O / dimethylformamide / 1 h / 50 °C

2: ethanol / 24 h / Heating

With hydrazine hydrate; In ethanol; N,N-dimethyl-formamide;