4-(Benzyloxy)benzimidamide hydrochloride

Base Information

• Chemical Name: 4-(Benzyloxy)benzimidamide hydrochloride
• CAS No.: 57928-60-6
• Molecular Formula: C14H14N2O
• Molecular Weight: 226.27
• Hs Code.: 2925290090
• European Community (EC) Number: 831-682-5
• DSSTox Substance ID: DTXSID80459895
• ChEMBL ID: CHEMBL2286481
• Mol file: 57928-60-6.mol

Synonyms:57928-60-6;4-(BENZYLOXY)BENZIMIDAMIDE HYDROCHLORIDE;4-(benzyloxy)benzene-1-carboximidamide hydrochloride;4-BENZYLOXY-BENZAMIDINE HYDROCHLORIDE;4-Benzyloxybenzamidine hydrochloride;4-phenylmethoxybenzenecarboximidamide;hydrochloride;4-phenylmethoxybenzenecarboximidamide Hydrochloride;SCHEMBL1034406;CHEMBL2286481;DTXSID80459895;YYXKRNUJMKSJMF-UHFFFAOYSA-N;MFCD06738564;AKOS015846802;CS-0251658;4-(BENZYLOXY)BENZIMIDAMIDEHYDROCHLORIDE;EN300-55645;A831674;Z1259341025;4-(Benzyloxy)benzene-1-carboximidamide--hydrogen chloride (1/1)

Chemical Property of 4-(Benzyloxy)benzimidamide hydrochloride

Chemical Property:

• Melting Point: 181-182 °C(Solv: ethyl ether (60-29-7))
• PSA: 59.10000
• LogP: 4.15170
• Storage Temp.: Sealed in dry,Room Temperature
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 262.0872908
• Heavy Atom Count: 18
• Complexity: 241

Purity/Quality:

99% ^*data from raw suppliers

4-(Benzyloxy)benzimidamidehydrochloride 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=CC=C(C=C2)C(=N)N.Cl

Technology Process of 4-(Benzyloxy)benzimidamide hydrochloride

There total 3 articles about 4-(Benzyloxy)benzimidamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

4-benzyloxybenzonitrile (52805-36-4) → 4-benzyloxyphenylamidine hydrochloride (57928-60-6)

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1002/ejoc.200600060

Reference yield: 92.0%

→ 4-benzyloxyphenylamidine hydrochloride (57928-60-6)

Guidance literature:

Reference yield: 84.0%

4-benzyloxybenzonitrile (52805-36-4) → C14H14N2O*1.16ClH (57928-60-6)

Guidance literature:

4-benzyloxybenzonitrile; With hydrogenchloride; In ethanol; benzene; at 20 ℃; for 16h;

With ammonia; In ethanol; at 20 ℃; for 120h; Further stages.;

DOI:10.1021/jo702495u

upstream raw materials:

4-benzyloxybenzonitrile