6-(p-Tolyl)nicotinic acid

Base Information

Chemical Name:6-(p-Tolyl)nicotinic acid
CAS No.:521074-77-1
Molecular Formula:C₁₃H₁₁NO₂
Molecular Weight:213.236
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70603764
Nikkaji Number:J2.066.854G
Wikidata:Q82501280
Mol file:521074-77-1.mol

Synonyms:6-(p-Tolyl)nicotinic acid;521074-77-1;6-(4-Methylphenyl)nicotinic acid;6-(4-Methylphenyl)pyridine-3-carboxylic acid;6-(4-ETHYLPHENYL)-NICOTINIC ACID;6-(p-Tolyl)nicotinicacid;6-(4-METHYLPHENYL)-3-PYRIDINECARBOXYLIC ACID;SCHEMBL5428820;DTXSID70603764;SBZIVZCDYSNVSC-UHFFFAOYSA-N;MFCD06410399;AKOS016013436;AB24362;TS-03040;EN300-1628100

Suppliers and Price of 6-(p-Tolyl)nicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
6-(4-Methylphenyl)nicotinic acid 97%
1g
$ 488.00

Crysdot
6-(p-Tolyl)nicotinicacid 95+%
1g
$ 459.00

Chemenu
6-(4-Methylphenyl)nicotinicacid 95%
1g
$ 434.00

Atlantic Research Chemicals
6-(4-Methylphenyl)nicotinicacid 95%
1gm:
$ 187.33

American Custom Chemicals Corporation
6-(PARA-TOLYL)NICOTINIC ACID 95.00%
5MG
$ 497.53

Alichem
6-(p-Tolyl)nicotinicacid
1g
$ 477.92

AK Scientific
6-(4-Methylphenyl)nicotinicacid
1g
$ 708.00

Acrotein
6-(4-Methylphenyl)-3-pyridinecarboxylicacid 97%
0.5g
$ 293.34

Absolute Chiral
6-(p-tolyl)nicotinicacid 95%
100 mg
$ 198.00

Total 8 raw suppliers

Chemical Property of 6-(p-Tolyl)nicotinic acid

Chemical Property:

PSA：50.19000
LogP:3.00920
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:213.078978594
Heavy Atom Count:16
Complexity:246

Purity/Quality:

98%Min ^*data from raw suppliers

6-(4-Methylphenyl)nicotinic acid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=NC=C(C=C2)C(=O)O

Technology Process of 6-(p-Tolyl)nicotinic acid

There total 2 articles about 6-(p-Tolyl)nicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5326-23-8
6-Chloro-3-pyridinecarboxylic acid

: 5720-05-8
4-methylphenylboronic acid

: 521074-77-1
6-(4-methylphenyl)nicotinic acid

Guidance literature:: 6-Chloro-3-pyridinecarboxylic acid; With tritylchloride-polystyrene resin; N-ethyl-N,N-diisopropylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 18h;

4-methylphenylboronic acid; With potassium phosphate; phenyl-phospha-adamantane; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; In tetrahydrofuran; water; at 20 ℃; for 15h;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1.5h; Further stages.;
DOI:10.1016/j.tetlet.2004.05.110