4-Hydroxy-4-methylpyrrolidin-2-one

Base Information

Chemical Name:4-Hydroxy-4-methylpyrrolidin-2-one
CAS No.:53598-98-4
Molecular Formula:C5H9NO2
Molecular Weight:115.13
Hs Code.:2933790090
European Community (EC) Number:865-223-5
DSSTox Substance ID:DTXSID80379327
Nikkaji Number:J2.491.381C
Mol file:53598-98-4.mol

Synonyms:4-hydroxy-4-methylpyrrolidin-2-one;53598-98-4;SCHEMBL2790791;DTXSID80379327;4-Methyl-4-hydroxypyrrolidine-2-one;MFCD00111581;AKOS006221678;CS-13030;CS-0046662;FT-0692501;EN300-125031;F18103

Suppliers and Price of 4-Hydroxy-4-methylpyrrolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-hydroxy-4-methylpyrrolidin-2-one
5mg
$ 60.00

Crysdot
4-Hydroxy-4-methylpyrrolidin-2-one 95+%
250mg
$ 595.00

Chemenu
4-Hydroxy-4-methylpyrrolidin-2-one 95%
1g
$ 729.00

American Custom Chemicals Corporation
4-HYDROXY-4-METHYLPYRROLIDIN-2-ONE 95.00%
1G
$ 1148.48

Alichem
4-Hydroxy-4-methylpyrrolidin-2-one
1g
$ 634.28

Alichem
4-Hydroxy-4-methylpyrrolidin-2-one
250mg
$ 343.20

AK Scientific
4-Hydroxy-4-methylpyrrolidin-2-one
1g
$ 1633.00

AK Scientific
4-Hydroxy-4-methylpyrrolidin-2-one
100mg
$ 653.00

Total 20 raw suppliers

Chemical Property of 4-Hydroxy-4-methylpyrrolidin-2-one

Chemical Property:

Vapor Pressure:2.97E-05mmHg at 25°C
Melting Point:140 °C
Refractive Index:1.493
Boiling Point:95 °C
Flash Point:146.4°C
PSA：49.33000
Density:1.191g/cm³
LogP:-0.41390
Storage Temp.:2-8°C
XLogP3:-1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:115.063328530
Heavy Atom Count:8
Complexity:124

Purity/Quality:

97% ^*data from raw suppliers

4-hydroxy-4-methylpyrrolidin-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T

MSDS Files:

Useful:

Canonical SMILES:CC1(CC(=O)NC1)O

Technology Process of 4-Hydroxy-4-methylpyrrolidin-2-one

There total 4 articles about 4-Hydroxy-4-methylpyrrolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6330-37-6
ethyl 3-cyano-3-hydroxybutanoate

: 53598-98-4
4-Hydroxy-4-methyl-2-pyrrolidon

Guidance literature:: With nickel; acetic acid; at 100 ℃; under 88260.9 Torr; Hydrogenation;

Reference yield:

: 945257-34-1
C₂₁H₂₇O₃N

: 53598-98-4
4-Hydroxy-4-methyl-2-pyrrolidon

Guidance literature:: Multi-step reaction with 2 steps

1: H₂; conc. HCl / Pd/C / ethanol / 24 h / 20 °C / atmospheric pressure

2: aq. NH₃ / 3 h / 20 °C

With hydrogenchloride; ammonium hydroxide; hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1080/00397910701319023