6-CHLORO-3-METHYL-1-PHENYL-1H-PYRIMIDINE-2,4-DIONE

Base Information

Chemical Name:6-CHLORO-3-METHYL-1-PHENYL-1H-PYRIMIDINE-2,4-DIONE
CAS No.:53680-90-3
Molecular Formula:C11H9ClN2O2
Molecular Weight:236.658
Hs Code.:
DSSTox Substance ID:DTXSID00567486
Wikidata:Q82453383
Mol file:53680-90-3.mol

Synonyms:6-CHLORO-3-METHYL-1-PHENYL-1H-PYRIMIDINE-2,4-DIONE

Suppliers and Price of 6-CHLORO-3-METHYL-1-PHENYL-1H-PYRIMIDINE-2,4-DIONE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
6-CHLORO-3-METHYL-1-PHENYL-1H-PYRIMIDINE-2,4-DIONE 95.00%
5MG
$ 499.63

Total 7 raw suppliers

Chemical Property of 6-CHLORO-3-METHYL-1-PHENYL-1H-PYRIMIDINE-2,4-DIONE

Chemical Property:

PSA：44.00000
LogP:1.18960
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:236.0352552
Heavy Atom Count:16
Complexity:348

Purity/Quality:

99% ^*data from raw suppliers

6-CHLORO-3-METHYL-1-PHENYL-1H-PYRIMIDINE-2,4-DIONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=O)C=C(N(C1=O)C2=CC=CC=C2)Cl

Technology Process of 6-CHLORO-3-METHYL-1-PHENYL-1H-PYRIMIDINE-2,4-DIONE

There total 7 articles about 6-CHLORO-3-METHYL-1-PHENYL-1H-PYRIMIDINE-2,4-DIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 77-78-1
dimethyl sulfate

: 155700-29-1
6-chloro-1-phenylpyrimidine-2,4(1H,3H)-dione

: 53680-90-3
6-chloro-3-methyl-1-phenylpyrimidine-2,4(1H,3H)-dione

Guidance literature:: With caesium carbonate; In acetone; at 20 ℃; for 16h;
DOI:10.1016/j.bmcl.2013.08.111

Reference yield:

: 53727-29-0
1-phenyl-3-methyl-barbituric acid

: 53680-90-3
6-chloro-3-methyl-1-phenylpyrimidine-2,4(1H,3H)-dione

Guidance literature:: With trichlorophosphate; at 80 ℃;
DOI:10.1016/S0968-0896(00)00126-7

Reference yield:

: 42212-19-1
6-amino-3-methyl-1-phenylpyrimidine-2,4(1H,3H)dione

: 53680-90-3
6-chloro-3-methyl-1-phenylpyrimidine-2,4(1H,3H)-dione

Guidance literature:: Multi-step reaction with 2 steps

1: c-HCl / acetic acid / 80 °C

2: POCl₃ / 80 °C

With hydrogenchloride; trichlorophosphate; In acetic acid; 1: Oxidation / 2: Chlorination;
DOI:10.1016/S0968-0896(00)00126-7