5,8-Dichloro-4-hydroxyquinoline

Base Information

Chemical Name:5,8-Dichloro-4-hydroxyquinoline
CAS No.:53790-82-2
Molecular Formula:C9H5Cl2NO
Molecular Weight:214.05
Hs Code.:2933499090
DSSTox Substance ID:DTXSID80355863
Wikidata:Q82134923
Mol file:53790-82-2.mol

Synonyms:5,8-Dichloro-4-hydroxyquinoline;53790-82-2;5,8-dichloroquinolin-4-ol;5,8-dichloro-1H-quinolin-4-one;5,8-DICHLORO-4-QUINOLINOL;5,8-dichloroquinolin-4(1H)-one;DTXSID80355863;MFCD00272374;4(1H)-Quinolinone,?5,8-dichloro-;AB05645;FT-0619859;AE-406/41055812

Suppliers and Price of 5,8-Dichloro-4-hydroxyquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
5,8-DICHLORO-4-HYDROXYQUINOLINE 95.00%
5MG
$ 504.69

Total 7 raw suppliers

Chemical Property of 5,8-Dichloro-4-hydroxyquinoline

Chemical Property:

Vapor Pressure:0.000119mmHg at 25°C
Melting Point:256-257 °C
Refractive Index:1.62
Boiling Point:335.6°Cat760mmHg
PKA:7.37±0.42(Predicted)
Flash Point:156.8°C
PSA：33.12000
Density:1.466g/cm³
LogP:3.24720
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:212.9748192
Heavy Atom Count:13
Complexity:254

Purity/Quality:

98%min ^*data from raw suppliers

5,8-DICHLORO-4-HYDROXYQUINOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C2C(=C1Cl)C(=O)C=CN2)Cl

Technology Process of 5,8-Dichloro-4-hydroxyquinoline

There total 5 articles about 5,8-Dichloro-4-hydroxyquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 893597-99-4
5-{[(2,5-dichlorophenyl)amino]methylene}-2,2-dimethyl-1,3-dioxane-4,6-dione

: 53790-82-2,887572-40-9
5,8-dichloro-4-(1H)-oxoquinoline

Guidance literature:: In diphenylether; for 1h; Reflux;

Reference yield:

: 859981-90-1
5,8-dichloro-4-hydroxy-quinoline-2-carboxylic acid

: 53790-82-2
4-hydroxy-5,8-dichloroquinoline

Guidance literature:: With mineral oil; at 240 - 270 ℃;
DOI:10.1021/ja01211a030

Reference yield:

: 95-82-9
2,5 dichloroaniline

: 53790-82-2
4-hydroxy-5,8-dichloroquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: acetic acid / Erhitzen des Reaktionsprodukts in Mineraloel auf 250grad

2: aqueous NaOH

3: mineral oil / 240 - 270 °C

With sodium hydroxide; acetic acid; mineral oil;
DOI:10.1021/ja01211a030