Methyl 1-(methoxymethyl)-L-prolinate

Base Information

Chemical Name:Methyl 1-(methoxymethyl)-L-prolinate
CAS No.:53823-82-8
Molecular Formula:C8H15NO3
Molecular Weight:173.2096
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30501313
Nikkaji Number:J2.003.563C
Wikidata:Q82353616
Mol file:53823-82-8.mol

Synonyms:53823-82-8;Methyl 1-(methoxymethyl)-L-prolinate;DTXSID30501313;N-methoxymethyl-l-proline methyl ester;L-Proline,1-(methoxymethyl)-,methyl ester(9ci);(S)-Methyl 1-(methoxymethyl)pyrrolidine-2-carboxylate

Suppliers and Price of Methyl 1-(methoxymethyl)-L-prolinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 0 raw suppliers

Chemical Property of Methyl 1-(methoxymethyl)-L-prolinate

Chemical Property:

Boiling Point:65 °C(Press: 2 Torr)
PKA:6.39±0.40(Predicted)
PSA：38.77000
Density:1.073±0.06 g/cm3(Predicted)
LogP:0.16560
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:173.10519334
Heavy Atom Count:12
Complexity:160

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCN1CCCC1C(=O)OC
Isomeric SMILES:COCN1CCC[C@H]1C(=O)OC

Technology Process of Methyl 1-(methoxymethyl)-L-prolinate

There total 2 articles about Methyl 1-(methoxymethyl)-L-prolinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 2577-48-2
methyl (2S)-pyrrolidine carboxylate

: 107-30-2
chloromethyl methyl ether

: 53823-82-8
N-(methoxymethyl)-L-proline methyl ester

Guidance literature:: With triethylamine; In diethyl ether; at 20 ℃; for 2h;

Reference yield:

: 147-85-3,25191-13-3,37159-97-0,4305-67-3,4607-28-7
L-proline

: 53823-82-8
N-(methoxymethyl)-L-proline methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / Me₃SiCl / Heating

2: 47 percent / Et₃N / diethyl ether; diethyl ether / 2 h / 20 °C

With chloro-trimethyl-silane; triethylamine; In diethyl ether;