7-chloro-1H-imidazo[4,5-c]pyridin-4-amine

Base Information

• Chemical Name: 7-chloro-1H-imidazo[4,5-c]pyridin-4-amine
• CAS No.: 668268-69-7
• Molecular Formula: C6H5ClN4
• Molecular Weight: 168.58
• DSSTox Substance ID: DTXSID901270566
• Mol file: 668268-69-7.mol

Synonyms:7-chloro-1H-imidazo[4,5-c]pyridin-4-amine;668268-69-7;1H-Imidazo[4,5-c]pyridin-4-amine, 7-chloro-;7-chloro-3H-imidazo[4,5-c]pyridin-4-amine;SCHEMBL17253699;DTXSID901270566;AMY33996;MFCD18803252;AKOS025146823;SB11875;AS-34026;CS-0050054;1H-Imidazo[4,5-c]pyridin-4-amine, 7-chloro-;A867387

Chemical Property of 7-chloro-1H-imidazo[4,5-c]pyridin-4-amine

Chemical Property:

• PSA: 67.59000
• LogP: 1.77470
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 168.0202739
• Heavy Atom Count: 11
• Complexity: 154

Purity/Quality:

99%, ^*data from raw suppliers

7-Chloro-1H-Imidazo[4,5-c]pyridin-4-amine 97.0% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=C(C2=C(C(=N1)N)NC=N2)Cl

Technology Process of 7-chloro-1H-imidazo[4,5-c]pyridin-4-amine

There total 11 articles about 7-chloro-1H-imidazo[4,5-c]pyridin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.2%

3-deazaadenine (6811-77-4) → 8-chloro-3-deazaadenine (668268-64-2) + 3-chloro-3-deazaadenine (668268-69-7) + 2-chloro-3-deazaadenine (52559-17-8)

Guidance literature:

With hydrogenchloride; 3-chloro-benzenecarboperoxoic acid; In N,N-dimethyl acetamide; at 20 ℃; for 0.416667h;

DOI:10.1081/NCN-120026635

Reference yield:

2,6-dichloropyridine (2402-78-0) → 3-chloro-3-deazaadenine (668268-69-7)

Guidance literature:

Multi-step reaction with 11 steps

1: CF₃COOH; aq. H₂O₂ / 6.5 h / Heating

2: HNO₃; H₂SO₄ / 160 °C

3: AcOH; Fe / Heating

4: HNO₃; H₂SO₄ / 20 °C

5: H₂SO₄ / 100 °C

6: 51 percent / Fe / 2 h / Heating

7: aq. NaOH / Heating

8: 96 percent / Ac₂O / 4.5 h / Heating

9: 49 percent / ammonia / methanol / 90 h / 160 °C

10: 72 percent / NaOH; H₂ / Pd/C / H₂O / 20 h / 1758.3 Torr

11: 6.2 percent / HCl; mCPBA / N,N-dimethyl-acetamide / 0.42 h / 20 °C

With hydrogenchloride; sodium hydroxide; sulfuric acid; ammonia; hydrogen; dihydrogen peroxide; nitric acid; acetic anhydride; iron; acetic acid; 3-chloro-benzenecarboperoxoic acid; trifluoroacetic acid; palladium on activated charcoal; In methanol; N,N-dimethyl acetamide; water;

DOI:10.1081/NCN-120026635

Reference yield:

2,6-dichloro-[4]pyridylamine (2587-02-2) → 3-chloro-3-deazaadenine (668268-69-7)

Guidance literature:

Multi-step reaction with 8 steps

1: HNO₃; H₂SO₄ / 20 °C

2: H₂SO₄ / 100 °C

3: 51 percent / Fe / 2 h / Heating

4: aq. NaOH / Heating

5: 96 percent / Ac₂O / 4.5 h / Heating

6: 49 percent / ammonia / methanol / 90 h / 160 °C

7: 72 percent / NaOH; H₂ / Pd/C / H₂O / 20 h / 1758.3 Torr

8: 6.2 percent / HCl; mCPBA / N,N-dimethyl-acetamide / 0.42 h / 20 °C

With hydrogenchloride; sodium hydroxide; sulfuric acid; ammonia; hydrogen; nitric acid; acetic anhydride; iron; 3-chloro-benzenecarboperoxoic acid; palladium on activated charcoal; In methanol; N,N-dimethyl acetamide; water;

DOI:10.1081/NCN-120026635

upstream raw materials:

3-deazaadenine

3-amino-4-acetamido-2,6-dichloropyridine

2,6-dichloropyridine

2,6-dichloro-[4]pyridylamine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 668268-69-7 1H-Imidazo[4,5-c]pyridin-4-amine, 7-chloro-

Send

Send

Metric Ton KG G Pound L ML

Send

Send