Technology Process of Benzenesulfonic acid, 4-[[(4-amino-1,2,3,6-tetrahydro-2,6-dioxo-1-propyl-5-pyrimidinyl)amino]carbonyl]-, 3-nitrophenyl ester
There total 4 articles about Benzenesulfonic acid, 4-[[(4-amino-1,2,3,6-tetrahydro-2,6-dioxo-1-propyl-5-pyrimidinyl)amino]carbonyl]-, 3-nitrophenyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
methanol;
at 20 ℃;
DOI:10.1021/jm0310030
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Tris-HCl buffer; aq. NaOH / tetrahydrofuran / 4 h / 20 °C / pH 8 - 9
2: N-(3-(dimethylamino)propyl)-N-ethylcarbodiimide*HCl / methanol / 20 °C
With
sodium hydroxide; Tris-HCl buffer; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran; methanol;
DOI:10.1021/jm0310030
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Tris-HCl buffer; aq. NaOH / tetrahydrofuran / 4 h / 20 °C / pH 8 - 9
2: N-(3-(dimethylamino)propyl)-N-ethylcarbodiimide*HCl / methanol / 20 °C
With
sodium hydroxide; Tris-HCl buffer; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran; methanol;
DOI:10.1021/jm0310030
