Cyclopropanecarboxamidine

Base Information

• Chemical Name: Cyclopropanecarboxamidine
• CAS No.: 54070-74-5
• Molecular Formula: C4H9ClN2
• Molecular Weight: 84.1209
• Hs Code.: 2925290090
• Mol file: 54070-74-5.mol

Synonyms:Cyclopropanecarboxamidine Acetic Acid;

Chemical Property of Cyclopropanecarboxamidine

Chemical Property:

• Refractive Index: ">
• Boiling Point: 133.6 °C at 760 mmHg
• PKA: 12.10±0.20(Predicted)
• Flash Point: 34.6 °C
• PSA: 49.87000
• Density: 1.37±0.1 g/cm3(Predicted)
• LogP: 1.93440
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Cyclopropanecarboxamidine 95 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclopropanecarboxamidine

There total 2 articles about Cyclopropanecarboxamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cyclopropylcarboxamidine hydrochloride (57297-29-7,477904-80-6) → cyclopropanecarboxamidine (54070-74-5)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 0.25h;

Reference yield:

→ cyclopropanecarboxamidine (54070-74-5)

Guidance literature:

Cyclopropancarbonsaeure-amid-oxim, H2 an Rh-Al2O3 ;

Reference yield: 98.0%

cyclopropanecarboxamidine (54070-74-5) + 4,6-diphenyl-1,2,3,5-tetrazine → 2-cyclopropyl-4,6-diphenyl-1,3,5-triazine

Guidance literature:

In acetonitrile; at 25 ℃; for 2h; regioselective reaction;

DOI:10.1021/jacs.9b07744

upstream raw materials:

cyclopropylcarboxamidine hydrochloride

Downstream raw materials:

2-cyclopropyl-4-hydroxy-pyrimidine-5-carboxylic acid ethyl ester

2-cyclopropyl-5-fluoro-4,6-pyrimidinediol

2-cyclopropyl-4,6-dihydroxy-pyrimidine

C₁₅H₁₅IN₂

Refernces