(S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine

Base Information

Chemical Name:(S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine
CAS No.:62596-64-9
Molecular Formula:C₁₆H₁₇NO₂S
Molecular Weight:287.382
Hs Code.:2933990090
European Community (EC) Number:804-310-4
NSC Number:620181
DSSTox Substance ID:DTXSID40451032
Nikkaji Number:J1.091.968A
Mol file:62596-64-9.mol

Synonyms:(S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine;62596-64-9;(2S)-2-benzyl-1-(4-methylphenyl)sulfonylaziridine;(S)-2-Benzyl-1-tosylaziridine;NSC620181;(2S)-1-[(4-Methylphenyl)sulfonyl]-2-(phenylmethyl)aziridine;1-Tosyl-2beta-benzylaziridine;SCHEMBL3832918;DTXSID40451032;AKOS015913544;NSC-620181;(S)-2-Benzyl-1-(p-tolylsulfonyl)aziridin e;(S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine, 98%

Suppliers and Price of (S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine 98%
5g
$ 401.00

Sigma-Aldrich
(S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine 98%
1g
$ 109.00

American Custom Chemicals Corporation
(S)-(+)-2-BENZYL-1-(P-TOLYLSULFONYL)AZIRIDINE 95.00%
5G
$ 1144.23

American Custom Chemicals Corporation
(S)-(+)-2-BENZYL-1-(P-TOLYLSULFONYL)AZIRIDINE 95.00%
1G
$ 700.12

Total 8 raw suppliers

Chemical Property of (S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:92-94 °C(lit.)
Refractive Index:1.632
Boiling Point:434.381°C at 760 mmHg
Flash Point:216.506°C
PSA：45.53000
Density:1.271g/cm³
LogP:3.62930
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:287.09799996
Heavy Atom Count:20
Complexity:414

Purity/Quality:

98%,99%, ^*data from raw suppliers

(S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2CC2CC3=CC=CC=C3
Isomeric SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2C[C@@H]2CC3=CC=CC=C3
Uses (S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine can be used:To prepare tert-butyl(S)-6-((4-methylphenyl)sulfonamido)-3-oxo-7-phenylheptanoate, an intermediate for the synthesis of substituted octahydroindoles.In the preparation of ortho-bromo phenethylamine products, which are further used to synthesize chiral 2-substituted indolines.In the synthesis of β-aryltelluro?amines as potent carbonic anhydrase inhibitors.

Technology Process of (S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine

There total 17 articles about (S)-(+)-2-Benzyl-1-(p-tolylsulfonyl)aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: Diphenyl-phosphinic acid (S)-3-phenyl-2-(toluene-4-sulfonylamino)-propyl ester

: 71535-50-7,77210-52-7,62596-64-9
(S)-(+)-2-benzyl-1-(p-tolylsulfonyl)aziridine

Guidance literature:: With sodium hydride; In tetrahydrofuran;
DOI:10.1016/S0040-4020(97)10430-6

Reference yield: 93.0%

: 3182-95-4
L-Phenylalaninol

: 98-59-9
p-toluenesulfonyl chloride

: 71535-50-7,77210-52-7,62596-64-9
(S)-(+)-2-benzyl-1-(p-tolylsulfonyl)aziridine

Guidance literature:: With dmap; potassium carbonate; In dichloromethane; at 40 ℃; for 0.5h; optical yield given as %ee; Microwave irradiation;
DOI:10.1016/j.tetlet.2011.03.106

Reference yield: 51.0%

: 82495-70-3
(2S)-2-p-toluenesulfonamido-3-phenylpropanol

: 71535-50-7,77210-52-7,62596-64-9
(S)-(+)-2-benzyl-1-(p-tolylsulfonyl)aziridine

Guidance literature:: With sodium azide; di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃;
DOI:10.1016/j.bmc.2009.03.026