CIS-1,8-DIAMINO-P-METHANE

Base Information

• Chemical Name: CIS-1,8-DIAMINO-P-METHANE
• CAS No.: 54166-24-4
• Molecular Formula: C10H22N2
• Molecular Weight: 170.298
• Hs Code.: 2921300090
• Mol file: 54166-24-4.mol

Synonyms:CIS-1,8-DIAMINO-P-METHANE;cis-1,8-diamino-P-menthane

Chemical Property of CIS-1,8-DIAMINO-P-METHANE

Chemical Property:

• Vapor Pressure: 0.027mmHg at 25°C
• Refractive Index: 1.481
• Boiling Point: 246.5°Cat760mmHg
• Flash Point: 93.3°C
• PSA: 52.04000
• Density: 0.916g/cm³
• LogP: 3.03190

Purity/Quality:

98%,99%, ^*data from raw suppliers

cis-1,8-Diamino-p-menthane 98% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 23/24/25-34
• Safety Statements: 26-27-28-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of CIS-1,8-DIAMINO-P-METHANE

There total 1 articles about CIS-1,8-DIAMINO-P-METHANE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

(Z)-1,8-dinitro-p-menthane (54166-26-6) → (Z)-1,8-diamino-p-menthane (54166-24-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol; for 48h; under 760 Torr; Ambient temperature;

DOI:10.1021/jm00149a028

Reference yield: 61.2%

chloroform (67-66-3,8013-54-5) + (Z)-1,8-diamino-p-menthane (54166-24-4) → cis-1,8-diisocyano-p-menthane

Guidance literature:

(Z)-1,8-diamino-p-menthane; With 15-crown-5; sodium hydride; In benzene; at 40 - 50 ℃; for 0.25h;

chloroform; In benzene; at 40 ℃; for 1h;

DOI:10.1080/00397911.2012.666693

Reference yield:

4-(oxiranylmethoxy)-1H-indole (35308-87-3) + (Z)-1,8-diamino-p-menthane (54166-24-4) + 2-Bromoacetyl bromide (598-21-0) → N8-(bromoacetyl)-N1-<3-(4-indolyloxy)-2-hydroxypropyl>-(Z)-1,8-diamino-p-menthane (106469-51-6) + N1-(bromoacetyl)-N8-<3-(4-indolyloxy)-2-hydroxypropyl>-(Z)-1,8-diamino-p-menthane (106469-52-7)

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given; 1.) 70 deg C, 5 h, 2.) THF, 25 min;

DOI:10.1021/jm00387a005

upstream raw materials:

(Z)-1,8-dinitro-p-menthane

Downstream raw materials:

N⁸-<3-(o-allylphenoxy)-2-hydroxypropyl>-(Z)-1,8-diamino-p-menthane

N¹-<3-(o-allylphenoxy)-2-hydroxypropyl>-(Z)-1,8-diamino-p-menthane

N¹,N⁸-bis<3-(o-allylphenoxy)-2-hydroxypropyl>-(Z)-1,8-diamino-p-menthane

N⁸-<3-(o-allylphenoxy)-2-hydroxypropyl>-N¹-(bromoacetyl)-(Z)-1,8-diamino-p-menthane