2,6-Dimethylpyrimidine-4-carboxylic acid

Base Information

Chemical Name:2,6-Dimethylpyrimidine-4-carboxylic acid
CAS No.:54198-74-2
Molecular Formula:C7H8N2O2
Molecular Weight:152.15
Hs Code.:2933599090
European Community (EC) Number:891-608-2
Mol file:54198-74-2.mol

Synonyms:2,6-dimethylpyrimidine-4-carboxylic acid;54198-74-2;MFCD09755956;2,6-DIMETHYL-4-PYRIMIDINECARBOXYLIC ACID;2,6-Dimethylpyrimidine-4-carboxylic acid x0.3h2o;SCHEMBL1760306;MCFSYMKFEOQWAU-UHFFFAOYSA-N;AKOS011506173;SB56827;2,6-dimethylpyrimidine-4-carboxylicacid;BS-38193;SY180086;CS-0252724;EN300-61391;A18881;G37428;Z965072050

Suppliers and Price of 2,6-Dimethylpyrimidine-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,6-dimethylpyrimidine-4-carboxylicacid
100mg
$ 65.00

TRC
2,6-dimethylpyrimidine-4-carboxylicacid
50mg
$ 45.00

Matrix Scientific
2,6-Dimethyl-4-pyrimidinecarboxylic acid
10g
$ 1872.00

Matrix Scientific
2,6-Dimethyl-4-pyrimidinecarboxylic acid
5g
$ 1296.00

Matrix Scientific
2,6-Dimethyl-4-pyrimidinecarboxylic acid
1g
$ 540.00

ChemBridge Corporation
2,6-dimethylpyrimidine-4-carboxylicacid 95%
10 g
$ 596.00

American Custom Chemicals Corporation
2,6-DIMETHYLPYRIMIDINE-4-CARBOXYLIC ACID 95.00%
10G
$ 3122.84

American Custom Chemicals Corporation
2,6-DIMETHYLPYRIMIDINE-4-CARBOXYLIC ACID 95.00%
5G
$ 1976.78

American Custom Chemicals Corporation
2,6-DIMETHYLPYRIMIDINE-4-CARBOXYLIC ACID 95.00%
1G
$ 952.01

Total 10 raw suppliers

Chemical Property of 2,6-Dimethylpyrimidine-4-carboxylic acid

Chemical Property:

Vapor Pressure:0.000433mmHg at 25°C
Melting Point:191-192 °C(Solv: water (7732-18-5))
Refractive Index:1.558
Boiling Point:302.6°C at 760 mmHg
PKA:2.95±0.10(Predicted)
Flash Point:136.8°C
PSA：63.08000
Density:1.257g/cm³
LogP:0.79160
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:152.058577502
Heavy Atom Count:11
Complexity:161

Purity/Quality:

97% ^*data from raw suppliers

2,6-dimethylpyrimidine-4-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC(=N1)C)C(=O)O

Technology Process of 2,6-Dimethylpyrimidine-4-carboxylic acid

There total 5 articles about 2,6-Dimethylpyrimidine-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 103796-11-8
ethyl 2,6-dimethylpyrimidine-4-carboxylate

: 54198-74-2
2,6-dimethylpyrimidine-4-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol; at 20 ℃; for 2h;
DOI:10.1016/j.tet.2019.05.005

Reference yield:

: 64571-35-3
2,6-Dimethyl-4-pyrimidinecarbonitrile

: 54198-74-2
2,6-dimethylpyrimidine-4-carboxylic acid

Guidance literature:: With sodium hydroxide;
DOI:10.1007/BF00917846

Reference yield:

: ethyl 4-methoxy-2-oxo-3-pentenoate

: 54198-74-2
2,6-dimethylpyrimidine-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / acetonitrile / 2 h / 70 °C / Reflux

2: potassium hydroxide / ethanol / 2 h / 20 °C

With potassium carbonate; potassium hydroxide; In ethanol; acetonitrile;
DOI:10.1016/j.tet.2019.05.005