Cyclopentanecarboxylic acid, 2-(1-methylethyl)-, (1R,2S)- (9CI)

Base Information

Chemical Name:Cyclopentanecarboxylic acid, 2-(1-methylethyl)-, (1R,2S)- (9CI)
CAS No.:630390-23-7
Molecular Formula:C9H16O2
Molecular Weight:156.22214
Hs Code.:
Mol file:630390-23-7.mol

Synonyms:Cyclopentanecarboxylic acid, 2-(1-methylethyl)-, (1R,2S)- (9CI)

Suppliers and Price of Cyclopentanecarboxylic acid, 2-(1-methylethyl)-, (1R,2S)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Cyclopentanecarboxylic acid, 2-(1-methylethyl)-, (1R,2S)- (9CI)

Chemical Property:

PSA：37.30000
LogP:2.14330

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of Cyclopentanecarboxylic acid, 2-(1-methylethyl)-, (1R,2S)- (9CI)

There total 6 articles about Cyclopentanecarboxylic acid, 2-(1-methylethyl)-, (1R,2S)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 630390-22-6
(4S)-benzyl-3-[(1R,2S)-2-isopropyl-cyclopentanecarbonyl]-5,5-dimethyl-oxazolidin-2-one

: 630390-23-7
(1R,2S)-2-isopropyl-cyclopentanecarboxylic acid

Guidance literature:: With lithium hydroxide; dihydrogen peroxide; In tetrahydrofuran; water; at 0 - 20 ℃; for 4.5h;
DOI:10.1016/j.tetasy.2003.06.001

Reference yield:

: 90646-70-1
7-methyl-6-octenoic acid

: 630390-23-7
(1R,2S)-2-isopropyl-cyclopentanecarboxylic acid

Guidance literature:: Multi-step reaction with 6 steps

1.1: N-methyl morpholine / tetrahydrofuran / 0.02 h / 0 °C

2.1: NaH / tetrahydrofuran / 0.5 h / 0 °C

2.2: tetrahydrofuran / 10 h / 20 °C

3.1: Et₃N; Bu₂BOTf / CH₂Cl₂ / 1.25 h / -78 - 0 °C

3.2: 90 percent / N-bromosuccinimide / CH₂Cl₂ / 2 h / -78 °C

4.1: Yb(OTf)3 / diethyl ether / 0.5 h / 20 °C

4.2: 80 percent / Et₃B; O₂ / diethyl ether; hexane / 4 h / 0 °C

5.1: 84 percent / Bu₃SnH; Et₃B; O₂ / benzene; hexane / 12 h / 20 °C

6.1: 70 percent / H₂O₂; LiOH*H₂O / tetrahydrofuran; H₂O / 4.5 h / 0 - 20 °C

With 4-methyl-morpholine; lithium hydroxide; triethyl borane; di-n-butylboryl trifluoromethanesulfonate; dihydrogen peroxide; oxygen; tri-n-butyl-tin hydride; sodium hydride; triethylamine; ytterbium(III) triflate; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; water; benzene;
DOI:10.1016/j.tetasy.2003.06.001

Reference yield:

: C₁₄H₂₄O₄

: 630390-23-7
(1R,2S)-2-isopropyl-cyclopentanecarboxylic acid

Guidance literature:: Multi-step reaction with 5 steps

1.1: NaH / tetrahydrofuran / 0.5 h / 0 °C

1.2: tetrahydrofuran / 10 h / 20 °C

2.1: Et₃N; Bu₂BOTf / CH₂Cl₂ / 1.25 h / -78 - 0 °C

2.2: 90 percent / N-bromosuccinimide / CH₂Cl₂ / 2 h / -78 °C

3.1: Yb(OTf)3 / diethyl ether / 0.5 h / 20 °C

3.2: 80 percent / Et₃B; O₂ / diethyl ether; hexane / 4 h / 0 °C

4.1: 84 percent / Bu₃SnH; Et₃B; O₂ / benzene; hexane / 12 h / 20 °C

5.1: 70 percent / H₂O₂; LiOH*H₂O / tetrahydrofuran; H₂O / 4.5 h / 0 - 20 °C

With lithium hydroxide; triethyl borane; di-n-butylboryl trifluoromethanesulfonate; dihydrogen peroxide; oxygen; tri-n-butyl-tin hydride; sodium hydride; triethylamine; ytterbium(III) triflate; In tetrahydrofuran; diethyl ether; hexane; dichloromethane; water; benzene;
DOI:10.1016/j.tetasy.2003.06.001