Androst-5-en-17-one, 3-(acetyloxy)-7-hydroxy-, (3beta)- (9CI)

Base Information

• Chemical Name: Androst-5-en-17-one, 3-(acetyloxy)-7-hydroxy-, (3beta)- (9CI)
• CAS No.: 517894-20-1
• Molecular Formula: C21H30O4
• Molecular Weight: 346.4605
• Mol file: 517894-20-1.mol

Synonyms:Androst-5-en-17-one, 3-(acetyloxy)-7-hydroxy-, (3beta)- (9CI)

Chemical Property of Androst-5-en-17-one, 3-(acetyloxy)-7-hydroxy-, (3beta)- (9CI)

Chemical Property:

• PSA: 63.60000
• LogP: 3.42080

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Androst-5-en-17-one, 3-(acetyloxy)-7-hydroxy-, (3beta)- (9CI)

There total 15 articles about Androst-5-en-17-one, 3-(acetyloxy)-7-hydroxy-, (3beta)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-O-acetyl-7α-hydroxy-17,17-ethylenedioxy-DHEA → 3-O-acetyl-7α-OH-DHEA (37976-94-6,37976-96-8,517894-20-1)

Guidance literature:

With toluene-4-sulfonic acid; In water; acetone; at 20 ℃; for 24h;

Reference yield: 75.0%

prasterone acetate (853-23-6) → 3-O-acetyl-7-oxo-dehydroepiandrosterone (1449-61-2) + 7α-hydroxy-17-oxoandrost-5-ene-3β-yl acetate (37976-94-6,517894-20-1)

Guidance literature:

With tert.-butylhydroperoxide; manganese(IV) oxide; In dichloromethane; water; at -20 ℃; for 22h; regioselective reaction; Reflux;

DOI:10.1002/ejoc.201500829

Reference yield: 70.0%

3β-acetoxy-androst-5-en-7,17-dione (1449-61-2) → C21H32O4 + 3-O-acetyl-7α-OH-DHEA (37976-94-6,37976-96-8,517894-20-1)

Guidance literature:

3β-acetoxy-androst-5-en-7,17-dione; With L-Selectride; In tetrahydrofuran; at -78 ℃; for 5h;

With sodium hydroxide; dihydrogen peroxide; In water; at 0 - 20 ℃; for 30h;

upstream raw materials:

3β-acetoxy-androst-5-en-7,17-dione

prasterone acetate

7α-bromo-3β-(acetyloxy)androst-5-en-17-one

Acetic acid (3S,8R,9S,10R,13S,14S)-7-bromo-10,13-dimethyl-17-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl ester