Fmoc-(R)-3-Amino-3-(4-cyano-phenyl)-propionic acid

Base Information

Chemical Name:Fmoc-(R)-3-Amino-3-(4-cyano-phenyl)-propionic acid
CAS No.:517905-92-9
Molecular Formula:C₂₅H₂₀N₂O₄
Molecular Weight:412.445
Hs Code.:
DSSTox Substance ID:DTXSID00375881
Nikkaji Number:J2.066.209C
Wikidata:Q82164531
Mol file:517905-92-9.mol

Synonyms:517905-92-9;Fmoc-(R)-3-Amino-3-(4-cyano-phenyl)-propionic acid;(3R)-3-(4-cyanophenyl)-3-(9H-fluoren-9-ylmethoxycarbonylamino)propanoic acid;(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-cyanophenyl)propanoic acid;(3R)-3-(4-Cyanophenyl)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid;DTXSID00375881;MFCD03428044;AKOS015948761;PS-12450;CS-0181503;E82240;fmoc-(r)-3-amino-3-(4-cyanophenyl)propanoic acid;Fmoc-(R)-3-Amino-3-(4-cyanophenyl)propionic acid;(R)-beta-(9H-Fluorene-9-ylmethoxycarbonylamino)-4-cyanohydrocinnamic acid;(R)-3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-cyanophenyl)propanoicacid

Suppliers and Price of Fmoc-(R)-3-Amino-3-(4-cyano-phenyl)-propionic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chem-Impex
Fmoc-(R)-3-amino-3-(4-cyanophenyl)propionicacid
5G
$ 500.86

American Custom Chemicals Corporation
FMOC-(R)-3-AMINO-3-(4-CYANO-PHENYL)-PROPIONIC ACID 95.00%
5G
$ 1370.41

American Custom Chemicals Corporation
FMOC-(R)-3-AMINO-3-(4-CYANO-PHENYL)-PROPIONIC ACID 95.00%
1G
$ 751.91

Total 16 raw suppliers

Chemical Property of Fmoc-(R)-3-Amino-3-(4-cyano-phenyl)-propionic acid

Chemical Property:

PSA：99.42000
LogP:5.00368
XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:412.14230712
Heavy Atom Count:31
Complexity:671

Purity/Quality:

97% ^*data from raw suppliers

Fmoc-(R)-3-amino-3-(4-cyanophenyl)propionicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CC(=O)O)C4=CC=C(C=C4)C#N
Isomeric SMILES:C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@H](CC(=O)O)C4=CC=C(C=C4)C#N

Technology Process of Fmoc-(R)-3-Amino-3-(4-cyano-phenyl)-propionic acid

There total 8 articles about Fmoc-(R)-3-Amino-3-(4-cyano-phenyl)-propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 80971-95-5
(+/-)-3-amino-3-(4-cyanophenyl)propanoic acid

: 517905-92-9
(+/-)-3-(9-fluorenylmethoxycarbonylamino)-3-(4-cyanophenyl)propanoic acid

Guidance literature:: With sodium hydrogencarbonate; In water; acetone; at 0 - 20 ℃;
DOI:10.1016/j.tetasy.2004.05.012

Reference yield:

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 738606-24-1
(R)-3-amino-3-(4-cyanophenyl)propanoic acid

: 517905-92-9
(R)-3-(9-fluorenylmethoxycarbonylamino)-3-(4-cyanophenyl)propanoic acid

Guidance literature:: With sodium hydrogencarbonate; In water; acetone; at 0 - 20 ℃;
DOI:10.1016/j.tetasy.2004.05.012

Reference yield:

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 738606-23-0
ethyl (S)-3-butanoylamino-3-(4-cyanophenyl)propanoate

: 517905-92-9
(S)-3-(9-fluorenylmethoxycarbonylamino)-3-(4-cyanophenyl)propanoic acid

Guidance literature:: ethyl (S)-3-butanoylamino-3-(4-cyanophenyl)propanoate; With hydrogenchloride; for 3h;

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide; With sodium hydrogencarbonate; In water; acetone; at 0 - 20 ℃; Heating;
DOI:10.1016/j.tetasy.2004.05.012