Cyclobutanecarboxylic acid, 2-amino-, methyl ester, (1S,2R)- (9CI)

Base Information

Chemical Name:Cyclobutanecarboxylic acid, 2-amino-, methyl ester, (1S,2R)- (9CI)
CAS No.:517914-00-0
Molecular Formula:C6H11NO2
Molecular Weight:129.15704
Hs Code.:2922499990
Mol file:517914-00-0.mol

Synonyms:Cyclobutanecarboxylic acid, 2-amino-, methyl ester, (1S,2R)- (9CI)

Suppliers and Price of Cyclobutanecarboxylic acid, 2-amino-, methyl ester, (1S,2R)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 7 raw suppliers

Chemical Property of Cyclobutanecarboxylic acid, 2-amino-, methyl ester, (1S,2R)- (9CI)

Chemical Property:

PSA：52.32000
LogP:0.59700

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclobutanecarboxylic acid, 2-amino-, methyl ester, (1S,2R)- (9CI)

There total 3 articles about Cyclobutanecarboxylic acid, 2-amino-, methyl ester, (1S,2R)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 517913-98-3
methyl (1S,2R)-2-(((benzyloxy)carbonyl)amino)cyclobutane-1-carboxylate

: 517914-00-0
(1S,2R)-2-Amino-cyclobutanecarboxylic acid methyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 1520 Torr;
DOI:10.1016/S0957-4166(02)00652-3

Reference yield:

: 517913-99-4
(1S,2R)-2-(((benzyloxy)carbonyl)amino)cyclobutanecarboxylic acid

: 517914-00-0
(1S,2R)-2-Amino-cyclobutanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 100 percent / H₂ / 10 percent Pd/C / methanol / 1520 Torr

With hydrogen; palladium on activated charcoal; In methanol;
DOI:10.1016/S0957-4166(02)00652-3

Reference yield:

: 517913-95-0
tert-butyl (1S,2R)-2-(((benzyloxy)carbonyl)amino)cyclobutanecarboxylate

: 517914-00-0
(1S,2R)-2-Amino-cyclobutanecarboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / trifluoroacetic acid; triethylsilane / CH₂Cl₂ / 2 h / 20 °C

2: 100 percent / H₂ / 10 percent Pd/C / methanol / 1520 Torr

With triethylsilane; hydrogen; trifluoroacetic acid; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1016/S0957-4166(02)00652-3