Technology Process of 3-Chloro-5-isoxazoleacetic acid
There total 5 articles about 3-Chloro-5-isoxazoleacetic acid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: hydroxylammonium chloride, Na-acetate / H2O / 3 h
2: SOCl2 / diethyl ether / 0.5 h / Ambient temperature
3: acetic acid - 48percent HBr / 1.5 h / Heating
With
thionyl chloride; hydroxylamine hydrochloride; hydrogen bromide; sodium acetate; acetic acid;
In
diethyl ether; water;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: SOCl2 / diethyl ether / 0.5 h / Ambient temperature
2: acetic acid - 48percent HBr / 1.5 h / Heating
With
thionyl chloride; hydrogen bromide; acetic acid;
In
diethyl ether;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: CH3COOH, H2SO4 / H2O / 0.17 h / Heating
2: hydroxylammonium chloride, Na-acetate / H2O / 3 h
3: SOCl2 / diethyl ether / 0.5 h / Ambient temperature
4: acetic acid - 48percent HBr / 1.5 h / Heating
With
thionyl chloride; sulfuric acid; hydroxylamine hydrochloride; hydrogen bromide; sodium acetate; acetic acid;
In
diethyl ether; water;