6,8-Diazabicyclo[3.2.2]nonane-7,9-dione,1-methyl-3-methylene-,(1R,5R)-(9CI)

Base Information

Chemical Name:6,8-Diazabicyclo[3.2.2]nonane-7,9-dione,1-methyl-3-methylene-,(1R,5R)-(9CI)
CAS No.:530125-23-6
Molecular Formula:C9H12N2O2
Molecular Weight:180.2
Hs Code.:
Mol file:530125-23-6.mol

Synonyms:6,8-Diazabicyclo[3.2.2]nonane-7,9-dione,1-methyl-3-methylene-,(1R,5R)-(9CI)

Suppliers and Price of 6,8-Diazabicyclo[3.2.2]nonane-7,9-dione,1-methyl-3-methylene-,(1R,5R)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 6,8-Diazabicyclo[3.2.2]nonane-7,9-dione,1-methyl-3-methylene-,(1R,5R)-(9CI)

Chemical Property:

PSA：58.20000
LogP:0.36730

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6,8-Diazabicyclo[3.2.2]nonane-7,9-dione,1-methyl-3-methylene-,(1R,5R)-(9CI)

There total 2 articles about 6,8-Diazabicyclo[3.2.2]nonane-7,9-dione,1-methyl-3-methylene-,(1R,5R)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 530125-09-8
(1R,5R,1'S)-6,8-bis(1'-phenylethyl)-7,9-dioxo-1-methyl-3-methylene-6,8-diazabicyclo[3.2.2]nonane

: 530125-23-6,530125-31-6
(1R,5R)-7,9-dioxo-1-methyl-3-methylene-6,8-diazabicyclo[3.2.2]nonane

Guidance literature:: With ammonia; lithium; In tetrahydrofuran; tert-butyl alcohol; at -60 ℃; for 0.0833333h;
DOI:10.1016/S0957-4166(02)00834-0

Reference yield:

: 530125-05-4
(1R,5R,1'S)-6,8-bis(1'-phenylethyl)-7,9-dioxo-3-methylene-6,8-diazabicyclo[3.2.2]nonane

: 530125-23-6,530125-31-6
(1R,5R)-7,9-dioxo-1-methyl-3-methylene-6,8-diazabicyclo[3.2.2]nonane

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / MeLi / tetrahydrofuran / -78 - 20 °C

2: 92 percent / Li; NH₃ / tetrahydrofuran; 2-methyl-propan-2-ol / 0.08 h / -60 °C

With ammonia; methyllithium; lithium; In tetrahydrofuran; tert-butyl alcohol;
DOI:10.1016/S0957-4166(02)00834-0