Methyl 1-benzylpiperidine-3-carboxylate

Base Information

Chemical Name:Methyl 1-benzylpiperidine-3-carboxylate
CAS No.:50585-91-6
Molecular Formula:C₁₄H₁₉NO₂
Molecular Weight:233.31
Hs Code.:2933399090
DSSTox Substance ID:DTXSID80434940
Mol file:50585-91-6.mol

Synonyms:Methyl 1-benzylpiperidine-3-carboxylate;50585-91-6;METHYL 1-BENZYL-PIPERIDINE-3-CARBOXYLATE;3-Piperidinecarboxylic acid, 1-(phenylmethyl)-, methyl ester;AMY2424;DTXSID80434940;MFCD15146668;AKOS015949538;CS-W001582;DS-18562;FT-0685230;EN300-84150;1-benzyl-piperidine-3-carboxylic acid methyl ester;J-521750;Z1070566434

Suppliers and Price of Methyl 1-benzylpiperidine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl1-Benzylpiperidine-3-carboxylate
100mg
$ 60.00

Matrix Scientific
Methyl 1-benzylpiperidine-3-carboxylate >95%
5g
$ 1750.00

Matrix Scientific
Methyl 1-benzylpiperidine-3-carboxylate >95%
1g
$ 454.00

Crysdot
Methyl1-benzylpiperidine-3-carboxylate 95+%
10g
$ 193.00

Ambeed
Methyl1-benzylpiperidine-3-carboxylate 98+%
5g
$ 89.00

Alichem
Methyl1-benzylpiperidine-3-carboxylate
10g
$ 190.55

AK Scientific
Methyl1-benzylpiperidine-3-carboxylate
1g
$ 84.00

Total 17 raw suppliers

Chemical Property of Methyl 1-benzylpiperidine-3-carboxylate

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Refractive Index:1.538
Boiling Point:310.755 °C at 760 mmHg
Flash Point:108.437 °C
PSA：29.54000
Density:1.093 g/cm³
LogP:2.00950
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:233.141578849
Heavy Atom Count:17
Complexity:249

Purity/Quality:

97% ^*data from raw suppliers

Methyl1-Benzylpiperidine-3-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1CCCN(C1)CC2=CC=CC=C2

Technology Process of Methyl 1-benzylpiperidine-3-carboxylate

There total 6 articles about Methyl 1-benzylpiperidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 14376-92-2
(E/Z)-methyl 3-(benzylamino)acrylate

: 50585-91-6
1-benzylpiperidine-3-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: tetrahydrofuran / 16 h / 66 °C

2: 98 percent / H₂, Na₂CO₃ / 10percent Pd/C / ethanol / 2280 Torr

3: 99 percent / Lawesson's reagent / tetrahydrofuran

5: 1.) PrMgBr, 2.) NaBH₄

With Lawessons reagent; sodium tetrahydroborate; hydrogen; n-propylmagnesium bromide; sodium carbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1021/jo00092a015

Reference yield:

: 156779-10-1
1,4,5,6-tetrahydro-6-oxo-1-(phenylmethyl)-3-pyridinecarboxylic acid methyl ester

: 50585-91-6
1-benzylpiperidine-3-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 98 percent / H₂, Na₂CO₃ / 10percent Pd/C / ethanol / 2280 Torr

2: 99 percent / Lawesson's reagent / tetrahydrofuran

4: 1.) PrMgBr, 2.) NaBH₄

With Lawessons reagent; sodium tetrahydroborate; hydrogen; n-propylmagnesium bromide; sodium carbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1021/jo00092a015

Reference yield:

: 100-46-9
benzylamine

: 50585-91-6
1-benzylpiperidine-3-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: diethyl ether / 12 h / Ambient temperature

2: tetrahydrofuran / 16 h / 66 °C

3: 98 percent / H₂, Na₂CO₃ / 10percent Pd/C / ethanol / 2280 Torr

4: 99 percent / Lawesson's reagent / tetrahydrofuran

6: 1.) PrMgBr, 2.) NaBH₄

With Lawessons reagent; sodium tetrahydroborate; hydrogen; n-propylmagnesium bromide; sodium carbonate; palladium on activated charcoal; In tetrahydrofuran; diethyl ether; ethanol;
DOI:10.1021/jo00092a015