eptazocine

Base Information

• Chemical Name: eptazocine
• CAS No.: 54782-51-3
• Molecular Formula: C15H21NO
• Molecular Weight: 231.33
• Mol file: 54782-51-3.mol

Synonyms:1,6-Methano-1H-4-benzazonin-10-ol, 2,3,4,5,6,7-hexahydro-1,4-dimethyl-

Chemical Property of eptazocine

Chemical Property:

• PSA: 23.47000
• LogP: 2.48570

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of eptazocine

There total 6 articles about eptazocine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C22H25NO2 → (±)-eptazocine (54782-51-3)

Guidance literature:

With perchloric acid; palladium on activated charcoal; hydrogen; In ethanol; at 65 ℃; for 24h; under 30402 Torr;

Reference yield:

(-)-1,4-dimethyl-7-hydroxy-10-methoxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine (54782-11-5,74958-14-8,74958-15-9,74958-16-0) → (±)-eptazocine (54782-51-3)

Guidance literature:

With phosphorus; hydrogen iodide; In water; acetic acid;

Reference yield:

C20H22O2 → (±)-eptazocine (54782-51-3)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium cyanoborohydride / methanol / 12 h / 20 °C

2.1: acetic acid; chromium(VI) oxide / water / 2 h / 20 °C

2.2: 1 h / 20 °C

2.3: 16 h / 55 °C

3.1: palladium on activated charcoal; perchloric acid; hydrogen / ethanol / 24 h / 65 °C / 30402 Torr

With chromium(VI) oxide; perchloric acid; palladium on activated charcoal; hydrogen; sodium cyanoborohydride; acetic acid; In methanol; ethanol; water;

upstream raw materials:

(-)-1,4-dimethyl-7-hydroxy-10-methoxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benzazonine

Downstream raw materials:

(±)-eptazocine hydrobromide