3-(6-(Trifluoromethyl)pyridin-3-yl)propanoic acid

Base Information

• Chemical Name: 3-(6-(Trifluoromethyl)pyridin-3-yl)propanoic acid
• CAS No.: 539855-70-4
• Molecular Formula: C9H8F3NO2
• Molecular Weight: 219.1605296
• Hs Code.: 2933399090
• European Community (EC) Number: 942-840-9,672-873-1
• DSSTox Substance ID: DTXSID40382630
• Wikidata: Q82173984
• Mol file: 539855-70-4.mol

Synonyms:539855-70-4;3-[6-(trifluoromethyl)pyridin-3-yl]propanoic Acid;3-(6-(trifluoromethyl)pyridin-3-yl)propanoic acid;3-[6-(trifluoromethyl)-3-pyridyl]propionic acid;3-[2-(Trifluoromethyl)pyridin-5-yl]propanoic acid;3-Pyridinepropanoic acid, 6-(trifluoromethyl)-;MFCD06801326;3-[6-(Trifluoromethyl)-3-pyridyl]propionicAcid;3-(6-(trifluoromethyl)pyridine-3-yl)propanoic acid;SCHEMBL2948639;DTXSID40382630;AKOS015853102;CS-12292;SY045801;CS-0308976;O10875;EN300-1457375;A829887;3-(6-trifluoromethyl-pyridin-3-yl)-propionic acid

Chemical Property of 3-(6-(Trifluoromethyl)pyridin-3-yl)propanoic acid

Chemical Property:

• Melting Point: 94-98
• Boiling Point: 296.5±35.0 °C(Predicted)
• PKA: 4.34±0.10(Predicted)
• PSA: 50.19000
• Density: 1.368±0.06 g/cm3(Predicted)
• LogP: 2.11760
• Storage Temp.: 2-8°C
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 219.05071298
• Heavy Atom Count: 15
• Complexity: 230

Purity/Quality:

98%min ^*data from raw suppliers

3-[2-(Trifluoromethyl)pyridin-5-yl]propanoic acid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=NC=C1CCC(=O)O)C(F)(F)F

Technology Process of 3-(6-(Trifluoromethyl)pyridin-3-yl)propanoic acid

There total 1 articles about 3-(6-(Trifluoromethyl)pyridin-3-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(6-trifluoromethyl-pyridin-3-yl)-propionic acid methyl ester (871224-67-8) → 3-(6-trifluoromethyl-pyridin-3-yl)-propionic acid (539855-70-4)

Guidance literature:

3-(6-trifluoromethyl-pyridin-3-yl)-propionic acid methyl ester; With lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 20h;

With hydrogenchloride; In tetrahydrofuran; dichloromethane; water;

Reference yield: 76.0%

3-(6-trifluoromethyl-pyridin-3-yl)-propionic acid (539855-70-4) → C9H6F3NO2 (773131-93-4,944805-93-0)

Guidance literature:

With 6-(quinolin-2-yl)pyridin-2(1H)-one; sodium acetate; palladium diacetate; lithium carbonate; silver carbonate; In 1,4-dioxane; tert-Amyl alcohol; at 110 ℃; for 16h; Inert atmosphere;

DOI:10.1126/science.abl3939

upstream raw materials:

3-(6-trifluoromethyl-pyridin-3-yl)-propionic acid methyl ester

Downstream raw materials:

C₉H₆F₃NO₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 539855-70-4 3-[2-(Trifluoromethyl)pyridin-5-yl]propanoic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send