PIPERAZINE-1-CARBOXYLIC ACID ALLYL ESTER

Base Information

• Chemical Name: PIPERAZINE-1-CARBOXYLIC ACID ALLYL ESTER
• CAS No.: 55389-48-5
• Molecular Formula: C8H14N2O2
• Molecular Weight: 170.21
• Hs Code.: 2933599090
• Mol file: 55389-48-5.mol

Synonyms:PIPERAZINE-1-CARBOXYLIC ACID ALLYL ESTER

Chemical Property of PIPERAZINE-1-CARBOXYLIC ACID ALLYL ESTER

Chemical Property:

• PSA: 41.57000
• LogP: 0.48090
• Storage Temp.: 2-8°C(protect from light)

Purity/Quality:

98%min ^*data from raw suppliers

Piperazine-1-carboxylicacidallylester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of PIPERAZINE-1-CARBOXYLIC ACID ALLYL ESTER

There total 4 articles about PIPERAZINE-1-CARBOXYLIC ACID ALLYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-allyl 4-tert-butyl piperazine-1,4-dicarboxylate (705962-13-6) → N-(allyloxycarbonyl)-1,4-piperazine (55389-48-5)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 3h;

Reference yield: 85.0%

1-allyl 4-(2-oxo-2-phenylethyl) piperazine-1,4-dicarboxylate → N-(allyloxycarbonyl)-1,4-piperazine (55389-48-5)

Guidance literature:

With potassium phosphate; tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; ascorbic acid; In water; acetonitrile; at 20 ℃; for 2h; Sealed tube; Irradiation; Inert atmosphere;

DOI:10.1021/acs.joc.8b00096

Reference yield: 79.0%

Piperazine-1,4-dicarboxylic acid allyl ester (E)-3-phenyl-allyl ester → N-(allyloxycarbonyl)-1,4-piperazine (55389-48-5)

Guidance literature:

With tetraethylammonium bromide; phenol; In acetonitrile; Electrochemical reaction;

DOI:10.1016/S0040-4039(03)00009-1

upstream raw materials:

1-allyl 4-tert-butyl piperazine-1,4-dicarboxylate

Refernces

• 1、 -. "FUMAGILLOL HETEROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING SAME". Paragraph 00308. . Retrieved 2017/03/08.
• 2、 Hansen, Jeff,Freeman, Stanley,Hudlicky, Tomas. "Selective electrochemical deprotection of cinnamyl ethers, esters, and carbamates". . p. 1575 - 1578. Retrieved 2007/10/03.