3-Cyclohexyl-1,2-oxazol-5-amine

Base Information

Chemical Name:3-Cyclohexyl-1,2-oxazol-5-amine
CAS No.:500766-46-1
Molecular Formula:C9H14N2O
Molecular Weight:166.223
Hs Code.:2934999090
European Community (EC) Number:857-449-8
Mol file:500766-46-1.mol

Synonyms:3-cyclohexyl-1,2-oxazol-5-amine;500766-46-1;3-Cyclohexylisoxazol-5-amine;5-amino-3-cyclohexylisoxazole;MFCD10693350;SCHEMBL2795016;VQZCMFOELVYEHV-UHFFFAOYSA-N;AKOS005200631;AM803962;AS-61912;SY176129;EN300-54228;A871676;Z360168606

Suppliers and Price of 3-Cyclohexyl-1,2-oxazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-cyclohexyl-1,2-oxazol-5-amine
100mg
$ 175.00

Crysdot
3-Cyclohexylisoxazol-5-amine 95+%
5g
$ 1841.00

Crysdot
3-Cyclohexylisoxazol-5-amine 95+%
1g
$ 612.00

Chemenu
3-Cyclohexylisoxazol-5-amine 95%
1g
$ 578.00

Chemenu
3-Cyclohexylisoxazol-5-amine 95%
5g
$ 1734.00

American Custom Chemicals Corporation
3-CYCLOHEXYL-1,2-OXAZOL-5-AMINE 95.00%
5G
$ 1759.28

American Custom Chemicals Corporation
3-CYCLOHEXYL-1,2-OXAZOL-5-AMINE 95.00%
2.5G
$ 1363.65

American Custom Chemicals Corporation
3-CYCLOHEXYL-1,2-OXAZOL-5-AMINE 95.00%
1G
$ 925.31

AK Scientific
3-Cyclohexyl-1,2-oxazol-5-amine
100mg
$ 448.00

Total 2 raw suppliers

Chemical Property of 3-Cyclohexyl-1,2-oxazol-5-amine

Chemical Property:

Boiling Point:328.4±30.0 °C(Predicted)
PKA:-0.77±0.50(Predicted)
PSA：52.05000
Density:1.116±0.06 g/cm3(Predicted)
LogP:2.88570
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:166.110613074
Heavy Atom Count:12
Complexity:146

Purity/Quality:

97% ^*data from raw suppliers

3-cyclohexyl-1,2-oxazol-5-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC(CC1)C2=NOC(=C2)N

Technology Process of 3-Cyclohexyl-1,2-oxazol-5-amine

There total 3 articles about 3-Cyclohexyl-1,2-oxazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 62455-70-3
3-cyclohexyl-3-oxopropanenitrile

: 500766-46-1
3-cyclohexyl-5-aminoisoxazole

Guidance literature:: With hydroxylamine hydrochloride; sodium acetate; In methanol; at 20 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.8b00971

Reference yield:

: 3289-28-9
ethyl cyclohexanecarboxylate

: 500766-46-1
3-cyclohexyl-5-aminoisoxazole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / mineral oil; tetrahydrofuran / 50 °C

2: sodium hydroxide; hydroxylamine hydrochloride / water / 100 °C

With hydroxylamine hydrochloride; sodium hydride; sodium hydroxide; In tetrahydrofuran; water; mineral oil;
DOI:10.1016/j.bmc.2020.115742