Carbamic acid, (4-chloro-2-butenyl)-, 1,1-dimethylethyl ester (9CI)

Base Information

• Chemical Name: Carbamic acid, (4-chloro-2-butenyl)-, 1,1-dimethylethyl ester (9CI)
• CAS No.: 558443-28-0
• Molecular Formula: C9H16ClNO2
• Molecular Weight: 205.68184
• Mol file: 558443-28-0.mol

Synonyms:Carbamic acid, (4-chloro-2-butenyl)-, 1,1-dimethylethyl ester (9CI)

Chemical Property of Carbamic acid, (4-chloro-2-butenyl)-, 1,1-dimethylethyl ester (9CI)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbamic acid, (4-chloro-2-butenyl)-, 1,1-dimethylethyl ester (9CI)

There total 8 articles about Carbamic acid, (4-chloro-2-butenyl)-, 1,1-dimethylethyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

di-tert-butyl dicarbonate (24424-99-5) + <(Z)-4-chloro-2-butenyl>ammonium chloride (7153-66-4) → cis-tert-butoxycarbonyl-4-chloro-2-butenyl-1-amine (123642-28-4,558443-28-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃; for 6h;

DOI:10.1055/s-0035-1561608

Reference yield: 80.0%

(Z)-4-chlorobut-2-en-1-amine hydrochloride (54880-27-2) + di-tert-butyl dicarbonate (24424-99-5) → cis-tert-butoxycarbonyl-4-chloro-2-butenyl-1-amine (123642-28-4,558443-28-0)

Guidance literature:

(Z)-4-chlorobut-2-en-1-amine hydrochloride; di-tert-butyl dicarbonate; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; water; for 2.5h;

With sodium hydrogencarbonate; In tetrahydrofuran; diethyl ether; water;

Reference yield: 50.0%

di-tert-butyl dicarbonate (24424-99-5) + <(Z)-4-chloro-2-butenyl>ammonium chloride (7153-66-4) → (Z)-N1-(1H-Benzimidazol-2-ylmethyl)-N1-5.6,7,8-tetrahydro-quinolin-8-yl-but-2-ene-1,4-diamine (Hydrochloride Salt) + (E)-1-chloro-4--2-butene (121030-33-9,558443-28-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; water;

upstream raw materials:

trans-1,2-dichloroethylene

di-tert-butyl dicarbonate

C₁₄H₂₄ClNO₄

iminodicarboxylic acid di-tert-butyl ester

Downstream raw materials:

(2E,4E)-1--5-(4'-methoxyphenyl)-2,4-pentadiene

(2Z,4E)-1--5-(4'-methoxyphenyl)-2,4-pentadiene

(2E,4E)-1--5-(4'-chlorophenyl)-2,4-pentadiene

(2Z,4E)-1--5-(4'-chlorophenyl)-2,4-pentadiene