Technology Process of Spiro[1,3-dioxolane-2,7(1H)-quinoline], 4a-ethyloctahydro-, (4aR,8aS)- (9CI)
There total 23 articles about Spiro[1,3-dioxolane-2,7(1H)-quinoline], 4a-ethyloctahydro-, (4aR,8aS)- (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 454 mg / NH3 / tetrahydrofuran / 20 °C
2: p-TsOH*H2O / benzene / 14 h / Heating
3: 152 mg / benzene / 6 h / Heating
4: 99 percent / H2 / PtO2 / ethanol / 12 h / 20 °C
5: LiAlH4 / tetrahydrofuran / 2 h / Heating
With
lithium aluminium tetrahydride; ammonia; hydrogen; toluene-4-sulfonic acid;
platinum(IV) oxide;
In
tetrahydrofuran; ethanol; benzene;
DOI:10.1021/ol034020s
- Guidance literature:
-
Multi-step reaction with 6 steps
1: (COCl)2 / CH2Cl2 / 2 h / 20 °C
2: 454 mg / NH3 / tetrahydrofuran / 20 °C
3: p-TsOH*H2O / benzene / 14 h / Heating
4: 152 mg / benzene / 6 h / Heating
5: 99 percent / H2 / PtO2 / ethanol / 12 h / 20 °C
6: LiAlH4 / tetrahydrofuran / 2 h / Heating
With
lithium aluminium tetrahydride; oxalyl dichloride; ammonia; hydrogen; toluene-4-sulfonic acid;
platinum(IV) oxide;
In
tetrahydrofuran; ethanol; dichloromethane; benzene;
DOI:10.1021/ol034020s
- Guidance literature:
-
Multi-step reaction with 4 steps
1: p-TsOH*H2O / benzene / 14 h / Heating
2: 152 mg / benzene / 6 h / Heating
3: 99 percent / H2 / PtO2 / ethanol / 12 h / 20 °C
4: LiAlH4 / tetrahydrofuran / 2 h / Heating
With
lithium aluminium tetrahydride; hydrogen; toluene-4-sulfonic acid;
platinum(IV) oxide;
In
tetrahydrofuran; ethanol; benzene;
DOI:10.1021/ol034020s
