Methyl 6-methoxy-2-(methylamino)nicotinate

Base Information

• Chemical Name: Methyl 6-methoxy-2-(methylamino)nicotinate
• CAS No.: 503000-88-2
• Molecular Formula: C9H12N2O3
• Molecular Weight: 196.206
• Hs Code.: 2933399090
• DSSTox Substance ID: DTXSID301161842
• Mol file: 503000-88-2.mol

Synonyms:503000-88-2;METHYL 6-METHOXY-2-(METHYLAMINO)NICOTINATE;METHYL 6-METHOXY-2-(METHYLAMINO)PYRIDINE-3-CARBOXYLATE;SCHEMBL2576373;DTXSID301161842;AKOS006306159;AB63643;FT-0763354;METHYL6-METHOXY-2-(METHYLAMINO)NICOTINATE;3-Pyridinecarboxylic acid, 6-methoxy-2-(methylamino)-, methyl ester;3-PYRIDINECARBOXYLIC ACID,6-METHOXY-2-(METHYLAMINO)-,METHYL ESTER

Chemical Property of Methyl 6-methoxy-2-(methylamino)nicotinate

Chemical Property:

• PSA: 60.45000
• LogP: 0.99150
• XLogP3: 1.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 196.08479225
• Heavy Atom Count: 14
• Complexity: 199

Purity/Quality:

98%min ^*data from raw suppliers

methyl6-methoxy-2-(methylamino)nicotinate 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNC1=C(C=CC(=N1)OC)C(=O)OC

Technology Process of Methyl 6-methoxy-2-(methylamino)nicotinate

There total 1 articles about Methyl 6-methoxy-2-(methylamino)nicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-6-methoxypyridine-3-carboxylic acid (503000-87-1) → methyl 6-methoxy-2-methylaminopyridine-3-carboxylate (503000-88-2)

Guidance literature:

Multi-step reaction with 3 steps

1: SOCl₂ / 5 h / Heating

2: 4.0 g / 1 h / Heating

3: 83 percent / ethanol; H₂O / 12 h / Heating

With thionyl chloride; In ethanol; water;

DOI:10.1021/jm020270n

upstream raw materials:

2-chloro-6-methoxypyridine-3-carboxylic acid