2H-Pyran-3-carboxylicacid,4-aminotetrahydro-,methylester(9CI)

Base Information

Chemical Name:2H-Pyran-3-carboxylicacid,4-aminotetrahydro-,methylester(9CI)
CAS No.:503166-53-8
Molecular Formula:C7H13NO3
Molecular Weight:159.185
Hs Code.:
Mol file:503166-53-8.mol

Synonyms:2H-Pyran-3-carboxylicacid,4-aminotetrahydro-,methylester(9CI)

Suppliers and Price of 2H-Pyran-3-carboxylicacid,4-aminotetrahydro-,methylester(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 2H-Pyran-3-carboxylicacid,4-aminotetrahydro-,methylester(9CI)

Chemical Property:

Boiling Point:224.2±40.0 °C(Predicted)
PKA:8.91±0.40(Predicted)
PSA：61.55000
Density:1.115±0.06 g/cm3(Predicted)
LogP:0.22350

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2H-Pyran-3-carboxylicacid,4-aminotetrahydro-,methylester(9CI)

There total 2 articles about 2H-Pyran-3-carboxylicacid,4-aminotetrahydro-,methylester(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 127956-11-0
4-oxotetrahydro-2H-pyran-3-carboxylic acid methyl ester

: 503166-53-8,785776-21-8
methyl 4-aminotetrahydro-2H-pyran-3-carboxylate

Guidance literature:: 4-oxotetrahydro-2H-pyran-3-carboxylic acid methyl ester; With titanium(IV) isopropylate; ammonia; In methanol; at 50 ℃; for 3h; Sealed tube;

With sodium cyanoborohydride; In methanol; at 0 ℃; for 0.166667h;

Reference yield:

: 29943-42-8,143562-54-3
Tetrahydro-4H-pyran-4-one

: 503166-53-8,785776-21-8
methyl 4-aminotetrahydro-2H-pyran-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran

2.1: titanium(IV) isopropylate; ammonia / methanol / 3 h / 50 °C / Sealed tube

2.2: 0.17 h / 0 °C

With titanium(IV) isopropylate; ammonia; sodium hydride; In tetrahydrofuran; methanol;