2-chloro-N-cyclopentylpropanamide

Base Information

• Chemical Name: 2-chloro-N-cyclopentylpropanamide
• CAS No.: 565180-19-0
• Molecular Formula: C8H14ClNO
• Molecular Weight: 175.658
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID90403985
• Mol file: 565180-19-0.mol

Synonyms:2-chloro-N-cyclopentylpropanamide;565180-19-0;DTXSID90403985;MFCD03988563;AKOS000264002;AKOS016345636;LS-03125;UPCMLD0ENAT0517-5894:001;CS-0220094;FT-0679608;EN300-05748;Z56921832

Chemical Property of 2-chloro-N-cyclopentylpropanamide

Chemical Property:

• Vapor Pressure: 0.000438mmHg at 25°C
• Refractive Index: 1.481
• Boiling Point: 315.4°C at 760 mmHg
• Flash Point: 144.6°C
• PSA: 29.10000
• Density: 1.09g/cm³
• LogP: 2.06340
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 175.0763918
• Heavy Atom Count: 11
• Complexity: 143

Purity/Quality:

98%min ^*data from raw suppliers

2-chloro-N-cyclopentylpropanamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)NC1CCCC1)Cl

Technology Process of 2-chloro-N-cyclopentylpropanamide

There total 1 articles about 2-chloro-N-cyclopentylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-chloro-N-cyclopentylpropanamide (565180-19-0)

Guidance literature:

Reference yield: 90.0%

2-chloro-N-cyclopentylpropanamide (565180-19-0) + 1-chloromethyl-2-methylbenzene (552-45-4) → (442)T7119

Guidance literature:

1-chloromethyl-2-methylbenzene; With thiourea; In isopropyl alcohol; at 100 ℃; for 2h; Sealed tube;

2-chloro-N-cyclopentylpropanamide; With potassium hydroxide; In methanol; isopropyl alcohol; at 60 ℃; for 2h; Sonication;

DOI:10.1021/acscombsci.5b00024

Reference yield: 84.0%

2-chloro-N-cyclopentylpropanamide (565180-19-0) + 2-fluorobenzyl chloride (345-35-7) → N-cyclopentyl-2-((2-fluorobenzyl)thio)propanamide

Guidance literature:

2-fluorobenzyl chloride; With thiourea; In isopropyl alcohol; at 100 ℃; for 2h; Sealed tube;

2-chloro-N-cyclopentylpropanamide; With potassium hydroxide; In methanol; isopropyl alcohol; at 60 ℃; for 2h; Sonication;

DOI:10.1021/acscombsci.5b00024

Downstream raw materials:

N-cyclopentyl-2-(4-propionylpiperazin-1-yl)propanamide