3-Pyridinecarboxaldehyde, 5-(1-buten-1-yl)-4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-

Base Information

Chemical Name:3-Pyridinecarboxaldehyde, 5-(1-buten-1-yl)-4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-
CAS No.:503559-81-7
Molecular Formula:C29H32FNO2
Molecular Weight:445.57
Hs Code.:
Mol file:503559-81-7.mol

Synonyms:3-Pyridinecarboxaldehyde, 5-(1-buten-1-yl)-4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-

Suppliers and Price of 3-Pyridinecarboxaldehyde, 5-(1-buten-1-yl)-4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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American Custom Chemicals Corporation
5-(1-BUTEN-1-YL)-4-[4-FLUORO-2-(PHENYLMETHOXY)PHENYL]-2,6-BIS-(1-METHYLETHYL)-3-PYRIDINECARBOXALDEHYDE 95.00%
5MG
$ 497.26

Total 1 raw suppliers

Chemical Property of 3-Pyridinecarboxaldehyde, 5-(1-buten-1-yl)-4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-

Chemical Property:

Vapor Pressure:3.61E-12mmHg at 25°C
Refractive Index:1.583
Boiling Point:550.5°C at 760 mmHg
Flash Point:286.8°C
PSA：39.19000
Density:1.097g/cm³
LogP:7.94920

Purity/Quality:: 5-(1-BUTEN-1-YL)-4-[4-FLUORO-2-(PHENYLMETHOXY)PHENYL]-2,6-BIS-(1-METHYLETHYL)-3-PYRIDINECARBOXALDEHYDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Pyridinecarboxaldehyde, 5-(1-buten-1-yl)-4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)-

There total 9 articles about 3-Pyridinecarboxaldehyde, 5-(1-buten-1-yl)-4-[4-fluoro-2-(phenylmethoxy)phenyl]-2,6-bis(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: [4-(2-Benzyloxy-4-fluoro-phenyl)-5-((E)-but-1-enyl)-2,6-diisopropyl-pyridin-3-yl]-methanol

: 503559-81-7
4-(2-Benzyloxy-4-fluoro-phenyl)-5-((E)-but-1-enyl)-2,6-diisopropyl-pyridine-3-carbaldehyde

Guidance literature:: With pyridinium chlorochromate; In dichloromethane; at 20 ℃;
DOI:10.1016/S0960-894X(02)00736-9

Reference yield:

: 1830-54-2
3-oxopentanedioic acid dimethyl ester

: 503559-81-7
4-(2-Benzyloxy-4-fluoro-phenyl)-5-((E)-but-1-enyl)-2,6-diisopropyl-pyridine-3-carbaldehyde

Guidance literature:: Multi-step reaction with 9 steps

1: 64 percent / pyridine / 1,2-dichloro-ethane / 0 °C

2: 92 percent / NH₃ / methanol / 0 °C

3: 95 percent / K₂CO₃ / acetone / Heating

4: 78 percent / tetrahydrofuran / Heating

5: Red-Al<*> / tetrahydrofuran / 20 °C

6: PCC / CH₂Cl₂ / 20 °C

7: tetrahydrofuran / 20 °C

8: LiAlH₄ / tetrahydrofuran / 20 °C

9: PCC / CH₂Cl₂ / 20 °C

With pyridine; lithium aluminium tetrahydride; ammonia; potassium carbonate; sodium bis(2-methoxyethoxy)aluminium dihydride; pyridinium chlorochromate; In tetrahydrofuran; methanol; dichloromethane; 1,2-dichloro-ethane; acetone; 7: Wittig reaction;
DOI:10.1016/S0960-894X(02)00736-9

Reference yield:

: 470717-48-7
dimethyl 2,6-diisopropyl-4-oxo-2H-pyran-3,5-dicarboxylate

: 503559-81-7
4-(2-Benzyloxy-4-fluoro-phenyl)-5-((E)-but-1-enyl)-2,6-diisopropyl-pyridine-3-carbaldehyde

Guidance literature:: Multi-step reaction with 8 steps

1: 92 percent / NH₃ / methanol / 0 °C

2: 95 percent / K₂CO₃ / acetone / Heating

3: 78 percent / tetrahydrofuran / Heating

4: Red-Al<*> / tetrahydrofuran / 20 °C

5: PCC / CH₂Cl₂ / 20 °C

6: tetrahydrofuran / 20 °C

7: LiAlH₄ / tetrahydrofuran / 20 °C

8: PCC / CH₂Cl₂ / 20 °C

With lithium aluminium tetrahydride; ammonia; potassium carbonate; sodium bis(2-methoxyethoxy)aluminium dihydride; pyridinium chlorochromate; In tetrahydrofuran; methanol; dichloromethane; acetone; 6: Wittig reaction;
DOI:10.1016/S0960-894X(02)00736-9