(2,5-Dimethylphenyl)hydrazine

Base Information

• Chemical Name: (2,5-Dimethylphenyl)hydrazine
• CAS No.: 613-85-4
• Molecular Formula: C8H12N2
• Molecular Weight: 136.197
• Hs Code.: 2928000090
• DSSTox Substance ID: DTXSID30357397
• Nikkaji Number: J134.738A
• Wikidata: Q82137291
• Mol file: 613-85-4.mol

Synonyms:(2,5-dimethylphenyl)hydrazine;613-85-4;Hydrazine, (2,5-dimethylphenyl)-;2,5-dimethylphenylhydrazine;1-(2,5-dimethylphenyl)hydrazine;2.5-Dimethylphenylhydrazin;2,5-dimethyl-phenylhydrazine;SCHEMBL838148;DTXSID30357397;(2,5-Dimethyl-phenyl)-hydrazine;BBL022201;MFCD02656653;STK501156;AKOS004911134;A8111;BB 0249773;FT-0679184;F8889-2610

Chemical Property of (2,5-Dimethylphenyl)hydrazine

Chemical Property:

• PSA: 38.05000
• LogP: 2.36230
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 136.100048391
• Heavy Atom Count: 10
• Complexity: 103

Purity/Quality:

98%Min ^*data from raw suppliers

(2,5-Dimethylphenyl)hydrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)C)NN

Technology Process of (2,5-Dimethylphenyl)hydrazine

There total 7 articles about (2,5-Dimethylphenyl)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-Dimethylaniline (95-78-3) → (2,5-dimethylphenyl)hydrazine (613-85-4)

Guidance literature:

With hydrogenchloride; sodium nitrite; Diazotization_.man fuegt zu der Diazoniumsalzloesung Natriumsulfit, versetzt die Loesung mit Zinkstaub und Essigsaeure und zersetzt das entstandene Natriumsalz in waessr. Loesung mit Salzsaeure;

Reference yield:

2,5-dimethylphenyl tosylate (2493-58-5) → (2,5-dimethylphenyl)hydrazine (613-85-4)

Guidance literature:

With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; N-[2-(di(1-adamantyl)phosphino)phenyl]morpholine; hydrazine hydrate; sodium t-butanolate; In toluene; at 90 ℃; for 1h; Inert atmosphere; Glovebox;

DOI:10.1016/j.bmcl.2015.11.022

Reference yield:

→ (2,5-dimethylphenyl)hydrazine (613-85-4)

Guidance literature:

With hydrogenchloride; tin(ll) chloride;

DOI:10.1021/ja01335a063

upstream raw materials:

2,5-Dimethylaniline

2,5-dimethyl-benzenediazonium; chloride

mononitro-p-xylene

2,5-dimethylphenyl tosylate

Downstream raw materials:

acetic acid-[N'-(2,5-dimethyl-phenyl)-hydrazide]

1-(2,5-dimethyl-phenyl)-pyrazolidin-3-one

N-(2,5-dimethyl-phenyl)-N'-(2,4-dinitro-phenyl)-hydrazine

2-(2,5-dimethyl-phenylhydrazono)-propionic acid ethyl ester