3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propanoic Acid

Base Information

Chemical Name:3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propanoic Acid
CAS No.:662-22-6
Molecular Formula:C4H2F6O3
Molecular Weight:212.048
Hs Code.:2918199090
European Community (EC) Number:672-609-5
DSSTox Substance ID:DTXSID00369341
Nikkaji Number:J3.200.815A
Wikidata:Q27458379
Mol file:662-22-6.mol

Synonyms:662-22-6;2,2-Bis(trifluoromethyl)-2-hydroxyacetic acid;3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propanoic Acid;3,3,3-Trifluoro-2-hydroxy-2-(trifluoromethyl)propionic Acid;2,2-Bis(trifluoromethyl)glycolic acid;2,2-BIS(TRIFLUOROMETHYL)-2-HYDROXYACETICACID;2-Hydroxy-3,3,3-trifluoro-2-(trifluoromethyl)propionic acid;Propanoic acid, 3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)-;3,3,3-Trifluoro-2-hydroxy-2-trifluoromethylpropionic Acid;C4H2F6O3;4fp1;2,2-bis-trifluoromethyl 2-hydroxyacetic acid;SCHEMBL569050;DTXSID00369341;alpha-hydroxyperfluoroisobutyric acid;MFCD00190631;AKOS007930687;AS-81361;FT-0612531;T2587;2,2-bis-trifluoromethyl-2-hydroxyacetic acid;2,2-bis-trifluoromethyl-2-hydroxy-acetic acid;2-Hydroxy-2,2-bis(trifluoromethyl)acetic Acid;T72794;A835373;Q27458379;3,3,3-trifluoro-2-hydroxy-2-trifluoromethyl-propionic acid;3,3,3-trifluoro-2-hydroxy-2-trifluoromethylpropanoic acid;2-Hydroxy-2-(trifluoromethyl)-3,3,3-trifluoropropanoic acid;3,3,3-Trifluoro-2-hydroxy-2-(trifluoromethyl)propanoic acid, AldrichCPR;BFM

Suppliers and Price of 3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propanoic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,3,3-Trifluoro-2-hydroxy-2-(trifluoromethyl)propionic Acid
1g
$ 105.00

TRC
3,3,3-Trifluoro-2-hydroxy-2-(trifluoromethyl)propionic Acid
10g
$ 580.00

TCI Chemical
3,3,3-Trifluoro-2-hydroxy-2-(trifluoromethyl)propionic Acid >98.0%(T)
5g
$ 428.00

TCI Chemical
3,3,3-Trifluoro-2-hydroxy-2-(trifluoromethyl)propionic Acid >98.0%(T)
1g
$ 86.00

SynQuest Laboratories
3,3,3-Trifluoro-2-hydroxy-2-(trifluoromethyl)propionic acid 95%
25 g
$ 325.00

SynQuest Laboratories
3,3,3-Trifluoro-2-hydroxy-2-(trifluoromethyl)propionic acid 95%
1 g
$ 25.00

SynQuest Laboratories
3,3,3-Trifluoro-2-hydroxy-2-(trifluoromethyl)propionic acid 95%
5 g
$ 75.00

Matrix Scientific
2,2-Bis(trifluoromethyl)-2-hydroxyacetic acid 95+%
5g
$ 76.00

Matrix Scientific
2,2-Bis(trifluoromethyl)-2-hydroxyacetic acid 95+%
1g
$ 26.00

Matrix Scientific
2,2-Bis(trifluoromethyl)-2-hydroxyacetic acid 95+%
25g
$ 331.00

Total 18 raw suppliers

Chemical Property of 3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propanoic Acid

Chemical Property:

Vapor Pressure:0.00501mmHg at 25°C
Melting Point:30°C
Refractive Index:1.332
Boiling Point:153-156°C
PKA:0.84±0.22(Predicted)
Flash Point:153-156°C
PSA：57.53000
Density:1,183 g/cm3
LogP:0.92670
Storage Temp.:-20°C Freezer, Under inert atmosphere
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:1
Exact Mass:211.99081289
Heavy Atom Count:13
Complexity:201

Purity/Quality:

99%, ^*data from raw suppliers

3,3,3-Trifluoro-2-hydroxy-2-(trifluoromethyl)propionic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C,Xi
Statements: 34-36/37/38
Safety Statements: 26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(=O)(C(C(F)(F)F)(C(F)(F)F)O)O
Uses 3,3,3-Trifluoro-2-hydroxy-2-trifluoromethylpropionic Acid acts as a potent inhibitor of mandelate racemase with a novel binding mode.

Technology Process of 3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propanoic Acid

There total 8 articles about 3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propanoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: