4-Oxo-1,4-dihydro-pyridine-3-carboxylicacidethylester

Base Information

• Chemical Name: 4-Oxo-1,4-dihydro-pyridine-3-carboxylicacidethylester
• CAS No.: 10177-34-1
• Molecular Formula: C₈H₉NO₃
• Molecular Weight: 167.164
• Hs Code.: 2933399090
• Mol file: 10177-34-1.mol

Synonyms:Nicotinicacid, 1,4-dihydro-4-oxo-, ethyl ester (7CI,8CI)

Chemical Property of 4-Oxo-1,4-dihydro-pyridine-3-carboxylicacidethylester

Chemical Property:

• Melting Point: 226-227℃
• Boiling Point: 286℃
• Flash Point: 127℃
• PSA: 59.16000
• Density: 1.214
• LogP: 0.55160
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ethyl4-oxo-1,4-dihydropyridine-3-carboxylate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Oxo-1,4-dihydro-pyridine-3-carboxylicacidethylester

There total 2 articles about 4-Oxo-1,4-dihydro-pyridine-3-carboxylicacidethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 11.8%

1,3,5-Triazine (290-87-9) + ethyl acetoacetate (141-97-9) → pyrido<4,3-d>-pyrimidin-5(6H)one (74632-30-7) + ethyl 4-oxo-1,4-dihydro-3-pyridinecarboxylate (10177-34-1)

Guidance literature:

With sodium ethanolate; In ethanol; for 1h; Heating;

DOI:10.1002/jhet.5570170229

Reference yield:

→ ethyl 4-oxo-1,4-dihydro-3-pyridinecarboxylate (10177-34-1)

Guidance literature:

4-Chlor-nicotinsaeure, A.;

DOI:10.1039/j39660001816

upstream raw materials:

1,3,5-Triazine

ethyl acetoacetate

Refernces