4-Methyl-2-vinylpyridine

Base Information

• Chemical Name: 4-Methyl-2-vinylpyridine
• CAS No.: 13959-34-7
• Molecular Formula: C8H9N
• Molecular Weight: 119.166
• Hs Code.: 2933399090
• UNII: 8W3D1B5708
• DSSTox Substance ID: DTXSID20458605
• Nikkaji Number: J801.330F
• Wikidata: Q27896031
• Mol file: 13959-34-7.mol

Synonyms:4-Methyl-2-vinylpyridine;13959-34-7;2-Vinyl-4-picoline;2-ethenyl-4-methylpyridine;4-METHYL-2-VINYL-PYRIDINE;Pyridine, 2-ethenyl-4-methyl-;4-Picoline, 2-vinyl-;8W3D1B5708;2-vinyl-4-methylpyridine;SCHEMBL1282140;UNII-8W3D1B5708;DTXSID20458605;WVNIWWGCVMYYJZ-UHFFFAOYSA-N;AKOS006291279;SB53042;BS-49713;CS-0196764;A885970;J-007295;Q27896031

Chemical Property of 4-Methyl-2-vinylpyridine

Chemical Property:

• PSA: 12.89000
• LogP: 2.03300
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 119.073499291
• Heavy Atom Count: 9
• Complexity: 98.7

Purity/Quality:

99% ^*data from raw suppliers

4-METHYL-2-VINYLPYRIDINE 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=NC=C1)C=C

Technology Process of 4-Methyl-2-vinylpyridine

There total 5 articles about 4-Methyl-2-vinylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

2-Bromo-4-picoline (4926-28-7) + tri-n-butyl(vinyl)tin (7486-35-3) → 4-methyl-2-vinylpyridine (13959-34-7)

Guidance literature:

With 2,6-di-tert-butyl-4-methyl-phenol; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In toluene; at 100 ℃; for 18h;

Reference yield:

2-(4-methyl-pyridin-2-yl)-ethanol (4664-18-0) → 4-methyl-2-vinylpyridine (13959-34-7)

Guidance literature:

With potassium hydroxide;

Reference yield:

2,4-lutidine (108-47-4) → 4-methyl-2-vinylpyridine (13959-34-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 160 °C

2: potassium hydroxide

With potassium hydroxide;

upstream raw materials:

2-(4-methyl-pyridin-2-yl)-ethanol

2,4-lutidine

2-Bromo-4-picoline

tri-n-butyl(vinyl)tin

Downstream raw materials:

3-(4-Methyl-pyridin-2-yl)-1-phenyl-propan-1-one

1,4-Dimethyl-2-(2-benzoylethyl)pyridinium iodide

2-(2-Cyanethyl)-4-methylpyridin

2-(2-benzenesulfonyl-ethyl)-4-methyl-pyridine

Refernces

• 1、 -. "2-(1H-INDAZOL-6-YLAMINO)-BENZAMIDE COMPOUNDS AS PROTEIN KINASES INHIBITORS USEFUL FOR THE TREATMENT OF OPHTALMIC DISEASES". Page 64. . Retrieved 2010/02/07.