(2R,6S)-2,6-PIPERIDINEDICARBOXYLIC ACID DIMETHYL ESTER HYDROCHLORIDE

Base Information

Chemical Name:(2R,6S)-2,6-PIPERIDINEDICARBOXYLIC ACID DIMETHYL ESTER HYDROCHLORIDE
CAS No.:6039-37-8
Molecular Formula:C₉H₁₅NO₄
Molecular Weight:201.222
Hs Code.:
Mol file:6039-37-8.mol

Synonyms:(2R,6S)-2,6-PIPERIDINEDICARBOXYLIC ACID DIMETHYL ESTER HYDROCHLORIDE

Suppliers and Price of (2R,6S)-2,6-PIPERIDINEDICARBOXYLIC ACID DIMETHYL ESTER HYDROCHLORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (2R,6S)-2,6-PIPERIDINEDICARBOXYLIC ACID DIMETHYL ESTER HYDROCHLORIDE

Chemical Property:

PSA：64.63000
LogP:0.97390

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2R,6S)-2,6-PIPERIDINEDICARBOXYLIC ACID DIMETHYL ESTER HYDROCHLORIDE

There total 6 articles about (2R,6S)-2,6-PIPERIDINEDICARBOXYLIC ACID DIMETHYL ESTER HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: Pyridine-2,6-dicarboxylic acid dimethyl ester; hydrochloride

: 59234-46-7
dimethyl (2R,6S)-piperidine-2,6-dicarboxylate

: 6039-37-8,59234-46-7,98965-16-3
(2R,6R)-Piperidine-2,6-dicarboxylic acid dimethyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In water; for 15h; under 775.7 Torr; Ambient temperature;
DOI:10.1021/jo9519569

Reference yield:

: 499-83-2
Pyridine-2,6-dicarboxylic acid

: 6039-37-8,59234-46-7,98965-16-3
(2R,6R)-Piperidine-2,6-dicarboxylic acid dimethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 2,2-dimethoxypropane, HCl / 1.) reflux, 4 h, 2.) room temperature, overnight

2: hydrogen / palladium on carbon / H₂O / 15 h / 775.7 Torr / Ambient temperature

With hydrogenchloride; hydrogen; 2,2-dimethoxy-propane; palladium on activated charcoal; In water;
DOI:10.1021/jo9519569

Reference yield:

: 243868-68-0
dimethyl 1,4-dihydropyridine-2,6-dicarboxylate

: 6039-37-8
Piperidin-2,6-dicarbonsaeuredimethylester

: dimethyl 1,4,5,6-tetrahydropyridine-2,6-dicarboxylate

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; at 20 ℃; for 14h; Title compound not separated from byproducts;
DOI:10.1016/S0040-4020(01)00058-8