5a-Androst-3-en-17-one

Base Information

Chemical Name:5a-Androst-3-en-17-one
CAS No.:14935-81-0
Molecular Formula:C19H28 O
Molecular Weight:272.431
Hs Code.:
UNII:QR7BMS5XDS
ChEMBL ID:CHEMBL1629800
DSSTox Substance ID:DTXSID70473247
Metabolomics Workbench ID:35372
Nikkaji Number:J81.808I
Wikidata:Q27159128
Mol file:14935-81-0.mol

Synonyms:5alpha-androst-3-en-17-one;androst-3-en-17-one

Suppliers and Price of 5a-Androst-3-en-17-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 5a-Androst-3-en-17-one

Chemical Property:

PSA：17.07000
LogP:4.76430
XLogP3:4.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:272.214015512
Heavy Atom Count:20
Complexity:464

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC=CC1CCC3C2CCC4(C3CCC4=O)C
Isomeric SMILES:C[C@]12CCC=C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C

Technology Process of 5a-Androst-3-en-17-one

There total 10 articles about 5a-Androst-3-en-17-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 481-29-8
Epiandrosterone

: 14639-79-3,24174-20-7,82467-84-3,963-75-7
5α-androst-2-en-17-one

: 1156-86-1
3α-fluoro-5αH-androstan-17-one

: 14935-81-0
5α-androst-3-en-17β-ol

Guidance literature:: With N-tosyl-4-chlorobenzenesulfonimidoyl fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; In toluene; at 20 ℃; for 0.5h; Sealed tube;
DOI:10.1002/chem.201901176

Reference yield: 55.0%

: 481-29-8
Epiandrosterone

: 14639-79-3,24174-20-7,82467-84-3,963-75-7
5α-androst-2-en-17-one

: 14935-81-0
5α-androst-3-en-17β-ol

Guidance literature:: With diethylamino-sulfur trifluoride; In dichloromethane; at 0 ℃; for 1h; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.steroids.2012.07.012

Reference yield: 39.0%

: 10429-00-2
3α-(toluene-4-sulfonyloxy)-5α-androstan-17-one

: 14639-79-3,24174-20-7,82467-84-3,963-75-7
5α-androst-2-en-17-one

: 361-80-8
3β-fluoro-5αH-androstan-17-one

: 14935-81-0
5α-androst-3-en-17β-ol

Guidance literature:: With tetrabutylammonium difluorodimethylphenylsilicate; In acetonitrile; for 4h; stereoselective reaction; Reflux; Inert atmosphere;
DOI:10.1135/cccc20081825