6-amino-5-chloro-1-naphthol-3-sulfonic acid

Base Information

• Chemical Name: 6-amino-5-chloro-1-naphthol-3-sulfonic acid
• CAS No.: 6361-45-1
• Molecular Formula: C10H8ClNO4S
• Molecular Weight: 273.69282
• Hs Code.: 2922299090
• Mol file: 6361-45-1.mol

Synonyms:6-amino-5-chloro-1-naphthol-3-sulfonic acid

Chemical Property of 6-amino-5-chloro-1-naphthol-3-sulfonic acid

Chemical Property:

• PKA: -0.48±0.40(Predicted)
• PSA: 109.00000
• Density: 1.721±0.06 g/cm3(Predicted)
• LogP: 3.68970

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-amino-5-chloro-1-naphthol-3-sulfonic acid

There total 6 articles about 6-amino-5-chloro-1-naphthol-3-sulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

8-chloro-4-hydroxy-7-(toluene-4-sulfonylamino)-naphthalene-2-sulfonic acid → 7-amino-8-chloro-4-hydroxy-naphthalene-2-sulfonic acid (6361-45-1)

Guidance literature:

With sulfuric acid;

Reference yield:

6-amino-naphthalene-1,3-disulfonic acid (118-33-2,87309-33-9) → 7-amino-8-chloro-4-hydroxy-naphthalene-2-sulfonic acid (6361-45-1)

Guidance literature:

Multi-step reaction with 4 steps

1: sodium acetate

2: chlorine

3: potassium hydroxide / 150 - 180 °C

4: concentrated sulfuric acid

With potassium hydroxide; sulfuric acid; sodium acetate; chlorine;

Reference yield:

6-(toluene-4-sulfonylamino)-naphthalene-1,3-disulfonic acid → 7-amino-8-chloro-4-hydroxy-naphthalene-2-sulfonic acid (6361-45-1)

Guidance literature:

Multi-step reaction with 3 steps

1: chlorine

2: potassium hydroxide / 150 - 180 °C

3: concentrated sulfuric acid

With potassium hydroxide; sulfuric acid; chlorine;

upstream raw materials:

4-hydroxy-7-acetylaminonaphthalene-2-sulphonic acid

p-toluenesulfonyl chloride

sulfuric acid

6-amino-naphthalene-1,3-disulfonic acid