1,2,5-Thiadiazol-3-amine

Base Information

• Chemical Name: 1,2,5-Thiadiazol-3-amine
• CAS No.: 6504-55-8
• Molecular Formula: C2H3 N3 S
• Molecular Weight: 101.13
• Hs Code.: 2934999090
• DSSTox Substance ID: DTXSID20447519
• Nikkaji Number: J881.249G
• Wikidata: Q82266394
• Mol file: 6504-55-8.mol

Synonyms:1,2,5-thiadiazol-3-amine;6504-55-8;1,2,5-Thiadiazol-3-amine(9CI);SCHEMBL2011621;DTXSID20447519;XIWSFHMGJRJKJR-UHFFFAOYSA-N;AKOS005186836;FT-0762493;EN300-148195

Chemical Property of 1,2,5-Thiadiazol-3-amine

Chemical Property:

• PSA: 80.04000
• LogP: 0.70150
• XLogP3: 0
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 0
• Exact Mass: 101.00476828
• Heavy Atom Count: 6
• Complexity: 48.1

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=NSN=C1N

Technology Process of 1,2,5-Thiadiazol-3-amine

There total 3 articles about 1,2,5-Thiadiazol-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3-Phthalimido-1,2,5-thiadiazole → 3-Amino-1,2,5-thiadiazole (6504-55-8)

Guidance literature:

With methylhydrazine; In benzene; for 0.166667h; Ambient temperature;

Reference yield:

acetimidamide (27757-71-7) → 3-Amino-1,2,5-thiadiazole (6504-55-8)

Guidance literature:

With disulfur dichloride; In N,N-dimethyl-formamide;

DOI:10.1021/jo01284a040

Reference yield:

→ 3-Amino-1,2,5-thiadiazole (6504-55-8)

Guidance literature:

3-Benzyloxyaminocarbonyl-1.2.5-thiadiazol IV,EtOH/HCl;

upstream raw materials:

acetimidamide

Downstream raw materials:

2-{2-[7-chloro-3-(3,5-dimethyl-phenyl)-2-oxo-6-([1,2,5]thiadiazol-3-ylcarbamoyl)-1,2-dihydro-quinolin-4-yloxy]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester