3,4-Dichlorobenzenesulfonohydrazide

Base Information

• Chemical Name: 3,4-Dichlorobenzenesulfonohydrazide
• CAS No.: 6655-74-9
• Molecular Formula: C6H6Cl2N2O2S
• Molecular Weight: 241.098
• Hs Code.: 2935009090
• DSSTox Substance ID: DTXSID90371054
• Wikidata: Q82158276
• ChEMBL ID: CHEMBL221706
• Mol file: 6655-74-9.mol

Synonyms:3,4-dichlorobenzenesulfonohydrazide;6655-74-9;3,4-Dichlorobenzenesulphonylhydrazide;3,4-dichlorobenzene-1-sulfonohydrazide;CHEMBL221706;Maybridge1_008871;SCHEMBL416745;HMS566L05;DTXSID90371054;BDBM50370865;MFCD01765419;AKOS009157815;AS-8125;CS-0317405;FT-0614229

Chemical Property of 3,4-Dichlorobenzenesulfonohydrazide

Chemical Property:

• Vapor Pressure: 1.38E-06mmHg at 25°C
• Melting Point: 120-124 (subl.)
• Refractive Index: 1.611
• Boiling Point: 399.3°C at 760 mmHg
• PKA: 8?+-.0.10(Predicted)
• Flash Point: 195.3°C
• PSA: 80.57000
• Density: 1.595g/cm³
• LogP: 3.31740
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 239.9527040
• Heavy Atom Count: 13
• Complexity: 264

Purity/Quality:

98%min ^*data from raw suppliers

3,4-Dichlorobenzenesulfonylhydrazide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1S(=O)(=O)NN)Cl)Cl

Technology Process of 3,4-Dichlorobenzenesulfonohydrazide

There total 1 articles about 3,4-Dichlorobenzenesulfonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3,4-dichlorobenzenesulphonyl chloride (98-31-7) → 3,4-dichlorobenzenesulfonohydrazide (6655-74-9)

Guidance literature:

In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1016/j.jfluchem.2013.01.033

Reference yield: 88.0%

3,4-dichlorobenzenesulfonohydrazide (6655-74-9) + 2-phenyl-α-azido-styrene → 6-(((3,4-dichlorophenyl)sulfonyl)methyl)phenanthridine

Guidance literature:

With tetrabutylammonium tetrafluoroborate; potassium carbonate; In water; acetonitrile; at 20 ℃; for 3h; Electrochemical reaction; Inert atmosphere; Green chemistry;

DOI:10.1002/ejoc.202001059

Reference yield: 81.0%

1-azidostyrene (16717-64-9) + 3,4-dichlorobenzenesulfonohydrazide (6655-74-9) → 2-((3,4-dichlorophenyl)sulfonyl)-1-phenylethan-1-one

Guidance literature:

1-azidostyrene; 3,4-dichlorobenzenesulfonohydrazide; With tetrabutylammonium tetrafluoroborate; In water; acetonitrile; at 20 ℃; for 2h; Electrochemical reaction; Inert atmosphere; Green chemistry;

With hydrogenchloride; water; In tetrahydrofuran; at 80 ℃; for 12h; Green chemistry;

DOI:10.1002/ejoc.202001059

upstream raw materials:

3,4-dichlorobenzenesulphonyl chloride

Downstream raw materials:

2-((3,4-dichlorophenyl)sulfonyl)-N-(1,1,1-trifluoro-2-(trifluoromethyl)butan-2-yl)hydrazine-1-carboxamide

tert-Butyl {1-[(3,4-dichlorophenyl)sulfonyl]-5-methyl-3-phenyl-1H-pyrazol-4-yl}acetate

Refernces

• 1、 Chen, Qianjin,Kong, Xianqiang,Li, Guodong,Liang, Qi,Lin, Long,Xu, Bo,Yu, Ke. "Metal-Free Electrochemical Coupling of Vinyl Azides: Synthesis of Phenanthridines and β-Ketosulfones". supporting information. p. 6135 - 6145. Retrieved 2020/10/06.