5-Hydroxy-2'-methoxyflavone

Base Information

Chemical Name:5-Hydroxy-2'-methoxyflavone
CAS No.:6665-71-0
Molecular Formula:C16H12O4
Molecular Weight:268.269
Hs Code.:2914509090
DSSTox Substance ID:DTXSID701222242
Wikidata:Q105192393
Metabolomics Workbench ID:23167
ChEMBL ID:CHEMBL2386666
Mol file:6665-71-0.mol

Synonyms:5-hydroxy-2'-methoxyflavone;6665-71-0;5-hydroxy-2-(2-methoxyphenyl)chromen-4-one;5-hydroxy-2-(2-methoxyphenyl)-4H-chromen-4-one;SCHEMBL4650059;CHEMBL2386666;DTXSID701222242;LMPK12110082;MFCD00017668;FT-0754661;5-Hydroxy-2-(2-methoxyphenyl)-4H-1-benzopyran-4-one

Suppliers and Price of 5-Hydroxy-2'-methoxyflavone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 5-Hydroxy-2'-methoxyflavone

Chemical Property:

Vapor Pressure:2.74E-09mmHg at 25°C
Refractive Index:1.641
Boiling Point:465.5°C at 760 mmHg
Flash Point:177.5°C
PSA：59.67000
Density:1.329g/cm³
LogP:3.17420
XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:268.07355886
Heavy Atom Count:20
Complexity:403

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1C2=CC(=O)C3=C(C=CC=C3O2)O

Technology Process of 5-Hydroxy-2'-methoxyflavone

There total 15 articles about 5-Hydroxy-2'-methoxyflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.5%

: C₁₈H₁₈O₅

: 6665-71-0
5-hydroxy-2-(2-methoxyphenyl)-4H-chromen-4-one

Guidance literature:: With iodine; In dimethyl sulfoxide; at 160 ℃; for 0.333333h;
DOI:10.1016/j.ejmech.2017.02.037

Reference yield: 67.0%

: 1443430-26-9
5-(benzyloxy)-2-(2-methoxyphenyl)-4H-chromen-4-one

: 6665-71-0
5-hydroxy-2-(2-methoxyphenyl)-4H-chromen-4-one

Guidance literature:: With acetic acid; In water; at 110 ℃; for 24h;
DOI:10.1021/jm4003457

Reference yield:

: 699-83-2
2,6-dihydroxylacetophenone

: 6665-71-0
5-hydroxy-2-(2-methoxyphenyl)-4H-chromen-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate; potassium iodide / acetone / Reflux; Inert atmosphere

2: potassium hydroxide / methanol / 19 h / 85 °C

3: iodine / dimethyl sulfoxide / 140 °C

4: acetic acid / water / 24 h / 110 °C

With iodine; potassium carbonate; acetic acid; potassium iodide; potassium hydroxide; In methanol; water; dimethyl sulfoxide; acetone;
DOI:10.1021/jm4003457